---
title: "Diagnostics & Epigenetic Tests — Evidence-Graded Longevity Products | Magellan"
description: "Evidence-graded diagnostics & epigenetic tests — 10 products, each linked to peer-reviewed research and PubMed citations."
url: "https://magellanlongevity.com/c/2.md"
canonical: "https://magellanlongevity.com/c/2.html"
html: "https://magellanlongevity.com/c/2.html"
type: "category"
section: "Diagnostics & Epigenetic Tests"
products: 10
citations: 185
updated: 2026-09-02
author: "Gabriel Radu, DO"
author_credentials: "Physiatrist (PM&R). NY medical license 275110. NPI 1376861765."
publisher: "Magellan Longevity"
content_format: "markdown"
---

# Diagnostics & Epigenetic Tests

[Home](https://magellanlongevity.com/) › Diagnostics & Epigenetic Tests

**HTML version:** https://magellanlongevity.com/c/2.html · **In the Magellan app:** https://magellanlongevity.com/#/cat/2

## What this category is

Every product below is graded on the strength of the human and mechanistic research behind it and linked to its primary PubMed citations — independent of affiliate commissions. 10 products, 185 distinct peer-reviewed citations in total.

## Evidence grade distribution

| Evidence grade | Products |
| --- | --- |
| Measurement tool | 9 |
| Preliminary | 1 |

## Every product in Diagnostics & Epigenetic Tests

| Product | Evidence grade | Citations | Typical price | Role |
| --- | --- | --- | --- | --- |
| [Grip-Strength Dynamometer](https://magellanlongevity.com/p/153.md) | Measurement tool | 16 | $45.00 | Across large prospective cohorts and meta-analyses, lower grip strength is consistently associated with higher… |
| [Saliva Cortisol Stress Test](https://magellanlongevity.com/p/149.md) | Preliminary | 17 | $129.95 | Across large studies, dysregulated cortisol patterns track with worse health: a meta-analysis found flatter daily… |
| [GGT Liver-Health Test](https://magellanlongevity.com/p/156.md) | Measurement tool | 22 | $40.00 | Large prospective cohorts and meta-analyses consistently link higher serum GGT, even within the reference range, to… |
| [Fasting Insulin / HOMA-IR Kit](https://magellanlongevity.com/p/145.md) | Measurement tool | 16 | $79.99 | Higher fasting insulin and HOMA-IR reflect greater insulin resistance, a central feature of metabolic syndrome that… |
| [hs-CRP Inflammation Test](https://magellanlongevity.com/p/142.md) | Measurement tool | 19 | $99.00 | Across large prospective cohorts and meta-analyses, higher hs-CRP is consistently associated with increased risk of… |
| [Omega-3 Index Test](https://magellanlongevity.com/p/143.md) | Measurement tool | 22 | $54.95 | In prospective cohort studies and pooled analyses spanning dozens of cohorts, higher blood levels of EPA + DHA have… |
| [Ferritin / Iron-Status Test](https://magellanlongevity.com/p/147.md) | Measurement tool | 18 | $99.00 | Iron status has a U-shaped relationship with health: iron deficiency (low ferritin) is a leading cause of anemia and,… |
| [Cystatin C / eGFR Kidney Test](https://magellanlongevity.com/p/157.md) | Measurement tool | 18 | $55.00 | Across large cohorts and meta-analyses, cystatin C-based eGFR is at least as accurate as creatinine-based eGFR and is… |
| [Lp(a) Mail-In Test](https://magellanlongevity.com/p/141.md) | Measurement tool | 19 | $152.00 | Large meta-analyses, prospective cohorts, and Mendelian randomization studies establish elevated Lp(a) as a causal,… |
| [ApoB Home Test Kit](https://magellanlongevity.com/p/140.md) | Measurement tool | 18 | $79.00 | Large Mendelian randomization studies, prospective cohorts and meta-analyses — in one pooling of 233,455 people apoB… |

## The research behind this category

The studies cited most often across the 10 products above. Quotes are verbatim from the cited abstract.

### Most-cited studies

1. **C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women**
   N Engl J Med 2000 · [PMID 10733371](https://pubmed.ncbi.nlm.nih.gov/10733371/) · [DOI 10.1056/NEJM200003233421202](https://doi.org/10.1056/NEJM200003233421202)

   > hs-CRP was the strongest univariate predictor of the risk of cardiovascular events

2. **Time-dependent associations between iron and mortality in hemodialysis patients**
   J Am Soc Nephrol 2005 · [PMID 16033854](https://pubmed.ncbi.nlm.nih.gov/16033854/) · [DOI 10.1681/ASN.2005040423](https://doi.org/10.1681/ASN.2005040423)

   > serum ferritin levels between 200 and 1200 ng/ml associated with the lowest all-cause and cardiovascular death risks

3. **Cortisol awakening response and psychosocial factors: a systematic review and meta-analysis.**
   Biological psychology 2009 · [PMID 19022335](https://pubmed.ncbi.nlm.nih.gov/19022335/)

   > Across 147 studies, the cortisol awakening response correlated positively with job and general life stress and negatively with fatigue, burnout, and exhaustion.

4. **Late-night salivary cortisol for the diagnosis of Cushing syndrome: a meta-analysis.**
   Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2009 · [PMID 19502211](https://pubmed.ncbi.nlm.nih.gov/19502211/)

   > Late-night salivary cortisol screens for Cushing syndrome with pooled 92% sensitivity and 96% specificity across 7 studies (947 patients).

5. **The association of biomarkers of iron status with mortality in US adults.**
   Nutrition, metabolism, and cardiovascular diseases : NMCD 2012 · [PMID 21330119](https://pubmed.ncbi.nlm.nih.gov/21330119/)

   > In NHANES III (n=12,258, up to 18 years of follow-up), ferritin and transferrin saturation within the normal range were not associated with all-cause, cardiovascular, or cancer mortality.

6. **A meta-analysis of low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B as markers of cardiovascular risk.**
   Circulation. Cardiovascular quality and outcomes 2011 · [PMID 21487090](https://pubmed.ncbi.nlm.nih.gov/21487090/)

   > In a meta-analysis of 233,455 people, apoB was the strongest lipid risk marker (relative-risk ratio 1.43 vs 1.34 for non-HDL-C and 1.25 for LDL-C), beating LDL-C by 12%.

7. **Contrasting associations of insulin resistance with diabetes, cardiovascular disease and all-cause mortality in the elderly: PROSPER**
   Diabetologia 2014 · [PMID 25264116](https://pubmed.ncbi.nlm.nih.gov/25264116/) · [DOI 10.1007/s00125-014-3383-9](https://doi.org/10.1007/s00125-014-3383-9)

   > Higher HOMA-IR was associated with incident diabetes

8. **Cystatin C estimated glomerular filtration rate and all-cause and cardiovascular disease mortality risk in the general population: AusDiab study.**
   Nephrology (Carlton, Vic.) 2017 · [PMID 26938304](https://pubmed.ncbi.nlm.nih.gov/26938304/)

   > In a general-population cohort, cystatin C-based eGFR independently predicted all-cause and cardiovascular mortality.

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## Related on Magellan Longevity

- [Nutraceuticals & Cellular Energizers](https://magellanlongevity.com/c/1.md)
- [Air, Water & Sleep Systems](https://magellanlongevity.com/c/3.md)
- [Biometric Wearables & Sensors](https://magellanlongevity.com/c/4.md)
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- [Longevity research map](https://magellanlongevity.com/longevity-research-map.html)

## Scope and disclosures

Educational information, not medical advice. Nothing here is intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement or device, especially if you are pregnant, nursing, or taking medication.

Editorial firewall: evidence grades are assigned from the published research and are independent of any affiliate commission. As an Amazon Associate, Magellan Longevity earns from qualifying purchases.

Reviewed for accuracy by a board-certified physician (DO).