---
title: "Omega-3 (EPA/DHA) — Evidence & Citations | Magellan"
description: "Natural sources, dosing and cited research for Omega-3 (EPA/DHA)."
url: "https://magellanlongevity.com/m/omega3.md"
canonical: "https://magellanlongevity.com/m/omega3.html"
html: "https://magellanlongevity.com/m/omega3.html"
type: "molecule"
slug: "omega3"
citations: 0
updated: 2026-08-11
author: "Gabriel Radu, DO"
author_credentials: "Physiatrist (PM&R). NY medical license 275110. NPI 1376861765."
publisher: "Magellan Longevity"
content_format: "markdown"
---

# Omega-3 (EPA/DHA)

[Home](https://magellanlongevity.com/) › Molecules › Omega-3 (EPA/DHA)

**HTML version:** https://magellanlongevity.com/m/omega3.html · **In the Magellan app:** https://magellanlongevity.com/#/search/Omega-3%20(EPA%2FDHA)

## Where it comes from without a bottle

Food, exercise and behaviour routes to the same pathway, each with its citation.

| Natural source | How it works | Citation |
| --- | --- | --- |
| Fatty fish (salmon, mackerel, sardines) | EPA/DHA from fatty fish; high fish intake is tied to ~50% lower sudden cardiac death. | Pharmacol Res 1999 [PMID 10479465](https://pubmed.ncbi.nlm.nih.gov/10479465/) |
| Walnuts & flaxseed (plant ALA) | Plant omega-3 (ALA) from walnuts/flax is linked to lower cardiovascular and fatal coronary risk. | Adv Nutr 2022 [PMID 35170723](https://pubmed.ncbi.nlm.nih.gov/35170723/) |

### What those papers actually say

1. **Fatty fish (salmon, mackerel, sardines)**
   Pharmacol Res 1999 · [PMID 10479465](https://pubmed.ncbi.nlm.nih.gov/10479465/) · [DOI 10.1006/phrs.1999.0495](https://doi.org/10.1006/phrs.1999.0495)

   > DHA is present in fatty fish (salmon, tuna, mackerel)... The reduction is approximately 50% with 200 mg/day of DHA from fish.

2. **Walnuts & flaxseed (plant ALA)**
   Adv Nutr 2022 · [PMID 35170723](https://pubmed.ncbi.nlm.nih.gov/35170723/) · [DOI 10.1093/advances/nmac016](https://doi.org/10.1093/advances/nmac016)

   > increasing dietary ALA is associated with a 10% lower risk of total cardiovascular disease and a 20% reduced risk of fatal coronary heart disease.

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## Related on Magellan Longevity

- [Evidence-based longevity supplements](https://magellanlongevity.com/longevity-supplements.md)
- [Longevity research map](https://magellanlongevity.com/longevity-research-map.html)
- [Pathway universe](https://magellanlongevity.com/pathway-universe.html)

## Scope and disclosures

Educational information, not medical advice. Nothing here is intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement or device, especially if you are pregnant, nursing, or taking medication.

Editorial firewall: evidence grades are assigned from the published research and are independent of any affiliate commission. As an Amazon Associate, Magellan Longevity earns from qualifying purchases.

Reviewed for accuracy by a board-certified physician (DO).