---
title: "Collagen supplementation in skin and orthopedic diseases: A…"
description: "Collagen supplementation may improve skin elasticity and hydration, reduce wrinkles, and enhance bone and joint health."
url: "https://magellanlongevity.com/study/collagen_review.md"
canonical: "https://magellanlongevity.com/study/collagen_review.html"
html: "https://magellanlongevity.com/study/collagen_review.html"
type: "study"
study_key: "collagen_review"
journal: "Heliyon"
year: 2023
pmid: "37064452"
doi: "10.1016/j.heliyon.2023.e14961"
citations: 1
updated: 2026-09-02
author: "Gabriel Radu, DO"
author_credentials: "Physiatrist (PM&R). NY medical license 275110. NPI 1376861765."
publisher: "Magellan Longevity"
content_format: "markdown"
---

# Collagen supplementation in skin and orthopedic diseases: A review of the literature

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**HTML version:** https://magellanlongevity.com/study/collagen_review.html · **In the Magellan app:** https://magellanlongevity.com/#/study/collagen_review

## Citation

| Field | Value |
| --- | --- |
| Journal | Heliyon |
| Year | 2023 |
| PMID | [37064452](https://pubmed.ncbi.nlm.nih.gov/37064452/) |
| DOI | [10.1016/j.heliyon.2023.e14961](https://doi.org/10.1016/j.heliyon.2023.e14961) |
| Study key | collagen_review |

## Takeaway

Collagen supplementation may improve skin elasticity and hydration, reduce wrinkles, and enhance bone and joint health.

## The question

What are the beneficial effects of collagen consumption in the treatment of skin and orthopedic diseases?

## Hypothesis

The study hypothesized that collagen supplementation would show beneficial effects on skin and orthopedic health.

## Methods

This study was a literature review, synthesizing existing scientific evidence on the effects of collagen consumption.

## Results

Collagen supplementation was found to decrease wrinkle formation, increase skin elasticity, hydration, and collagen content, density, and synthesis. For orthopedic health, it increased bone strength, density, and mass, improved joint stiffness/mobility and functionality, and reduced pain.

## Conclusion

Collagen supplementation demonstrates potential benefits for both skin and orthopedic health, addressing aging-related damage and issues from physical activity.

## Limitations

The abstract does not explicitly state any limitations of the review itself or the body of literature it synthesized.

## Verbatim from the abstract

> Collagen is one of the main components of the extracellular matrix of the dermis and articular cartilage and influences mechanical and tissue-formation properties.

## Where this study is used on Magellan

This paper is one of the citations behind the evidence grade on the pages below. Grades are assigned from the published research and are independent of affiliate commissions.

| Compound or device | Evidence grade | Graded pages |
| --- | --- | --- |
| Collagen Peptides | — | — |

## Reference

1. **Collagen supplementation in skin and orthopedic diseases: A review of the literature**
   Heliyon 2023 · [PMID 37064452](https://pubmed.ncbi.nlm.nih.gov/37064452/) · [DOI 10.1016/j.heliyon.2023.e14961](https://doi.org/10.1016/j.heliyon.2023.e14961)

   > Collagen is one of the main components of the extracellular matrix of the dermis and articular cartilage and influences mechanical and tissue-formation properties.

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## Scope and disclosures

Educational information, not medical advice. Nothing here is intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement or device, especially if you are pregnant, nursing, or taking medication.

Editorial firewall: evidence grades are assigned from the published research and are independent of any affiliate commission. As an Amazon Associate, Magellan Longevity earns from qualifying purchases.

Reviewed for accuracy by a board-certified physician (DO).