--- title: "Daily oral supplementation with collagen peptides combined with…" description: "A daily supplement with collagen peptides and other nutrients improved skin elasticity and joint health in a 90-day study." url: "https://magellanlongevity.com/study/collagen_skin.md" canonical: "https://magellanlongevity.com/study/collagen_skin.html" html: "https://magellanlongevity.com/study/collagen_skin.html" type: "study" study_key: "collagen_skin" journal: "Nutrition Research" year: 2018 pmid: "30122200" doi: "10.1016/j.nutres.2018.06.001" citations: 1 updated: 2026-09-02 author: "Gabriel Radu, DO" author_credentials: "Physiatrist (PM&R). NY medical license 275110. NPI 1376861765." publisher: "Magellan Longevity" content_format: "markdown" --- # Daily oral supplementation with collagen peptides combined with vitamins improves skin elasticity and has a beneficial effect on joint and general wellbeing [Home](https://magellanlongevity.com/) › [Research map](https://magellanlongevity.com/longevity-research-map.html) › Daily oral supplementation with collagen peptides combined… **HTML version:** https://magellanlongevity.com/study/collagen_skin.html · **In the Magellan app:** https://magellanlongevity.com/#/study/collagen_skin ## Citation | Field | Value | | --- | --- | | Journal | Nutrition Research | | Year | 2018 | | PMID | [30122200](https://pubmed.ncbi.nlm.nih.gov/30122200/) | | DOI | [10.1016/j.nutres.2018.06.001](https://doi.org/10.1016/j.nutres.2018.06.001) | | Study key | collagen_skin | ## Takeaway A daily supplement with collagen peptides and other nutrients improved skin elasticity and joint health in a 90-day study. ## The question Can daily oral supplementation with a liquid nutraceutical containing hydrolyzed fish collagen, vitamins, antioxidants, and other active ingredients improve skin texture and elasticity, and protect joint health? ## Hypothesis Daily oral supplementation with a liquid nutraceutical containing hydrolyzed fish collagen, vitamins, antioxidants, and other active ingredients could improve skin texture and elasticity, and have a protective effect on joint health. ## Methods A double-blind, randomized, placebo-controlled clinical trial was conducted over 90 days. 120 subjects were randomized to consume either the test product or a placebo daily. Skin elasticity was measured, and histological analysis of skin biopsies was performed. Self-perception questionnaires were used to assess skin hydration, elasticity, joint pain, and joint mobility. ## Results Subjects consuming the test product showed a significant increase in skin elasticity (+40%) compared to placebo. Histological analysis revealed positive changes in skin architecture, including reduced solar elastosis and improved collagen fiber organization. Self-perception questionnaires confirmed subjects' perceptions of more hydrated and elastic skin. The test product also reduced joint pain by -43% and improved joint mobility by +39%. ## Conclusion Oral supplementation with collagen bioactive peptides combined with chondroitin sulphate, glucosamine, L-carnitine, vitamins, and minerals significantly improved clinical parameters related to skin aging and joint health. ## Limitations The abstract does not explicitly state any limitations of the study. ## Verbatim from the abstract > Daily oral supplementation with collagen peptides improved skin elasticity and had a beneficial effect on joint and general wellbeing. ## Effects of Collagen Supplementation on Skin and Joint Health | Measure | Percentage Change | | --- | --- | | Skin Elasticity Increase | 40 | | Joint Pain Reduction | -43 | | Joint Mobility Improvement | 39 | *The test product group experienced a 40% increase in skin elasticity, a 43% reduction in joint pain, and a 39% improvement in joint mobility.* ## Where this study is used on Magellan This paper is one of the citations behind the evidence grade on the pages below. Grades are assigned from the published research and are independent of affiliate commissions. | Compound or device | Evidence grade | Graded pages | | --- | --- | --- | | Collagen Peptides | — | — | ## Reference 1. **Daily oral supplementation with collagen peptides combined with vitamins improves skin elasticity and has a beneficial effect on joint and general wellbeing** Nutrition Research 2018 · [PMID 30122200](https://pubmed.ncbi.nlm.nih.gov/30122200/) · [DOI 10.1016/j.nutres.2018.06.001](https://doi.org/10.1016/j.nutres.2018.06.001) > Daily oral supplementation with collagen peptides improved skin elasticity and had a beneficial effect on joint and general wellbeing. ## Structured data ```json {"@context":"https://schema.org","@graph":[{"@type":"MedicalWebPage","@id":"https://magellanlongevity.com/study/collagen_skin.html#page","url":"https://magellanlongevity.com/study/collagen_skin.html","name":"Daily oral supplementation with collagen peptides combined with vitamins improves skin elasticity and has a…","description":"A daily supplement with collagen peptides and other nutrients improved skin elasticity and joint health in a 90-day study.","inLanguage":"en","isPartOf":{"@type":"WebSite","name":"Magellan Longevity","url":"https://magellanlongevity.com/"},"author":{"@type":"Person","name":"Gabriel Radu, DO","jobTitle":"Physiatrist (PM&R)","identifier":[{"@type":"PropertyValue","name":"NPI","value":"1376861765"},{"@type":"PropertyValue","name":"NY medical license","value":"275110"}]},"publisher":{"@type":"Organization","name":"Magellan Longevity","url":"https://magellanlongevity.com/"},"encoding":{"@type":"MediaObject","encodingFormat":"text/markdown","contentUrl":"https://magellanlongevity.com/study/collagen_skin.md"},"dateModified":"2026-09-02"},{"@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://magellanlongevity.com/"},{"@type":"ListItem","position":2,"name":"Research map","item":"https://magellanlongevity.com/longevity-research-map.html"},{"@type":"ListItem","position":3,"name":"Daily oral supplementation with collagen peptides combined…","item":"https://magellanlongevity.com/study/collagen_skin.html"}]},{"@type":"ScholarlyArticle","@id":"https://magellanlongevity.com/study/collagen_skin.html#study","name":"Daily oral supplementation with collagen peptides combined with vitamins improves skin elasticity and has a beneficial effect on joint and general wellbeing","headline":"Daily oral supplementation with collagen peptides combined with vitamins improves skin elasticity and has a…","datePublished":"2018","isPartOf":{"@type":"Periodical","name":"Nutrition Research"},"identifier":"PMID:30122200","url":"https://pubmed.ncbi.nlm.nih.gov/30122200/","sameAs":"https://doi.org/10.1016/j.nutres.2018.06.001","abstract":"A daily supplement with collagen peptides and other nutrients improved skin elasticity and joint health in a 90-day study."}]} ``` ## Related on Magellan Longevity - [Collagen supplementation in skin and orthopedic diseases: A review of the literature](https://magellanlongevity.com/study/collagen_review.md) - [A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: a…](https://magellanlongevity.com/study/x7.md) - [Longevity research map](https://magellanlongevity.com/longevity-research-map.html) - [Evidence-based longevity supplements](https://magellanlongevity.com/longevity-supplements.md) ## Scope and disclosures Educational information, not medical advice. Nothing here is intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement or device, especially if you are pregnant, nursing, or taking medication. Editorial firewall: evidence grades are assigned from the published research and are independent of any affiliate commission. As an Amazon Associate, Magellan Longevity earns from qualifying purchases. Reviewed for accuracy by a board-certified physician (DO).