--- title: "Effect of quercetin supplementation on plasma lipid profiles,…" description: "Quercetin supplementation can lower blood pressure and may improve some lipid markers with longer-term use." url: "https://magellanlongevity.com/study/d31940027.md" canonical: "https://magellanlongevity.com/study/d31940027.html" html: "https://magellanlongevity.com/study/d31940027.html" type: "study" study_key: "d31940027" journal: "Nutr Rev" year: 2020 pmid: "31940027" doi: "10.1093/nutrit/nuz071" citations: 1 updated: 2026-09-02 author: "Gabriel Radu, DO" author_credentials: "Physiatrist (PM&R). NY medical license 275110. NPI 1376861765." publisher: "Magellan Longevity" content_format: "markdown" --- # Effect of quercetin supplementation on plasma lipid profiles, blood pressure, and glucose levels: a meta-analysis [Home](https://magellanlongevity.com/) › [Research map](https://magellanlongevity.com/longevity-research-map.html) › Effect of quercetin supplementation on plasma lipid… **HTML version:** https://magellanlongevity.com/study/d31940027.html · **In the Magellan app:** https://magellanlongevity.com/#/study/d31940027 ## Citation | Field | Value | | --- | --- | | Journal | Nutr Rev | | Year | 2020 | | PMID | [31940027](https://pubmed.ncbi.nlm.nih.gov/31940027/) | | DOI | [10.1093/nutrit/nuz071](https://doi.org/10.1093/nutrit/nuz071) | | Study key | d31940027 | ## Takeaway Quercetin supplementation can lower blood pressure and may improve some lipid markers with longer-term use. ## The question Does quercetin supplementation affect plasma lipid profiles, blood pressure, and glucose levels in humans? ## Hypothesis The study aimed to summarize evidence regarding the effects of quercetin supplementation on plasma lipid profiles, blood pressure, and glucose levels in humans. ## Methods A meta-analysis of randomized controlled trials was conducted. MEDLINE, Embase, and Scopus databases were searched from inception to July 2018. A random-effects model was used for data analysis, expressing continuous variables as weighted mean differences (WMDs) and 95%CIs. Subgroup and sensitivity analyses, as well as publication bias analyses, were also performed. ## Results Seventeen trials with a total of 896 participants were included. Quercetin significantly lowered systolic blood pressure by -3.09 mmHg and diastolic blood pressure by -2.86 mmHg. No significant changes were observed in overall lipid profiles or glucose concentrations. However, subgroup analyses showed significant changes in high-density lipoprotein cholesterol and triglycerides in trials with a parallel design where participants consumed quercetin for 8 weeks or more. ## Conclusion Quercetin intake significantly decreased blood pressure in humans. Additionally, high-density lipoprotein cholesterol and triglycerides levels were significantly changed in participants who consumed quercetin for 8 weeks or more in trials with a parallel design. ## Limitations The abstract does not explicitly state limitations of the meta-analysis itself, but notes that previous clinical trials reported conflicting results. ## Verbatim from the abstract > quercetin significantly lowered both systolic BP and diastolic BP ## Effect of Quercetin on Blood Pressure | Measure | Weighted Mean Difference (mmHg) | | --- | --- | | Systolic BP Reduction | -3.09 | | Diastolic BP Reduction | -2.86 | *Quercetin supplementation significantly reduced both systolic and diastolic blood pressure.* ## Where this study is used on Magellan This paper is one of the citations behind the evidence grade on the pages below. Grades are assigned from the published research and are independent of affiliate commissions. | Compound or device | Evidence grade | Graded pages | | --- | --- | --- | | Quercetin Capsules | Moderate evidence | [Quercetin Capsules](https://magellanlongevity.com/p/105.md) | ## Reference 1. **Effect of quercetin supplementation on plasma lipid profiles, blood pressure, and glucose levels: a meta-analysis** Nutr Rev 2020 · [PMID 31940027](https://pubmed.ncbi.nlm.nih.gov/31940027/) · [DOI 10.1093/nutrit/nuz071](https://doi.org/10.1093/nutrit/nuz071) > quercetin significantly lowered both systolic BP and diastolic BP ## Structured data ```json {"@context":"https://schema.org","@graph":[{"@type":"MedicalWebPage","@id":"https://magellanlongevity.com/study/d31940027.html#page","url":"https://magellanlongevity.com/study/d31940027.html","name":"Effect of quercetin supplementation on plasma lipid profiles, blood pressure, and glucose levels: a…","description":"Quercetin supplementation can lower blood pressure and may improve some lipid markers with longer-term use.","inLanguage":"en","isPartOf":{"@type":"WebSite","name":"Magellan Longevity","url":"https://magellanlongevity.com/"},"author":{"@type":"Person","name":"Gabriel Radu, DO","jobTitle":"Physiatrist (PM&R)","identifier":[{"@type":"PropertyValue","name":"NPI","value":"1376861765"},{"@type":"PropertyValue","name":"NY medical license","value":"275110"}]},"publisher":{"@type":"Organization","name":"Magellan Longevity","url":"https://magellanlongevity.com/"},"encoding":{"@type":"MediaObject","encodingFormat":"text/markdown","contentUrl":"https://magellanlongevity.com/study/d31940027.md"},"dateModified":"2026-09-02"},{"@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://magellanlongevity.com/"},{"@type":"ListItem","position":2,"name":"Research map","item":"https://magellanlongevity.com/longevity-research-map.html"},{"@type":"ListItem","position":3,"name":"Effect of quercetin supplementation on plasma lipid…","item":"https://magellanlongevity.com/study/d31940027.html"}]},{"@type":"ScholarlyArticle","@id":"https://magellanlongevity.com/study/d31940027.html#study","name":"Effect of quercetin supplementation on plasma lipid profiles, blood pressure, and glucose levels: a meta-analysis","headline":"Effect of quercetin supplementation on plasma lipid profiles, blood pressure, and glucose levels: a…","datePublished":"2020","isPartOf":{"@type":"Periodical","name":"Nutr Rev"},"identifier":"PMID:31940027","url":"https://pubmed.ncbi.nlm.nih.gov/31940027/","sameAs":"https://doi.org/10.1093/nutrit/nuz071","abstract":"Quercetin supplementation can lower blood pressure and may improve some lipid markers with longer-term use."}]} ``` ## Related on Magellan Longevity - [Quercetin Capsules](https://magellanlongevity.com/p/105.md) — product graded on this and related evidence - [Evidence: lowers systolic/diastolic blood pressure](https://magellanlongevity.com/study/s105.md) - [Effects of Quercetin on Blood Pressure: A Systematic Review and Meta-Analysis of…](https://magellanlongevity.com/study/d27405810.md) - [Senolytic drugs: from discovery to translation](https://magellanlongevity.com/study/d32686219.md) - [Longevity research map](https://magellanlongevity.com/longevity-research-map.html) - [Evidence-based longevity supplements](https://magellanlongevity.com/longevity-supplements.md) ## Scope and disclosures Educational information, not medical advice. Nothing here is intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement or device, especially if you are pregnant, nursing, or taking medication. Editorial firewall: evidence grades are assigned from the published research and are independent of any affiliate commission. As an Amazon Associate, Magellan Longevity earns from qualifying purchases. Reviewed for accuracy by a board-certified physician (DO).