--- title: "The Effects of Magnesium Supplementation on Blood Pressure Among…" description: "Magnesium supplementation can help lower blood pressure in people with type 2 diabetes, especially with higher doses or longer durations." url: "https://magellanlongevity.com/study/d32385715.md" canonical: "https://magellanlongevity.com/study/d32385715.html" html: "https://magellanlongevity.com/study/d32385715.html" type: "study" study_key: "d32385715" journal: "Biol Trace Elem Res" year: 2020 pmid: "32385715" doi: "10.1007/s12011-020-02157-0" citations: 1 updated: 2026-09-02 author: "Gabriel Radu, DO" author_credentials: "Physiatrist (PM&R). NY medical license 275110. NPI 1376861765." publisher: "Magellan Longevity" content_format: "markdown" --- # The Effects of Magnesium Supplementation on Blood Pressure Among Type 2 Diabetes Patients: a meta-analysis [Home](https://magellanlongevity.com/) › [Research map](https://magellanlongevity.com/longevity-research-map.html) › The Effects of Magnesium Supplementation on Blood Pressure… **HTML version:** https://magellanlongevity.com/study/d32385715.html · **In the Magellan app:** https://magellanlongevity.com/#/study/d32385715 ## Citation | Field | Value | | --- | --- | | Journal | Biol Trace Elem Res | | Year | 2020 | | PMID | [32385715](https://pubmed.ncbi.nlm.nih.gov/32385715/) | | DOI | [10.1007/s12011-020-02157-0](https://doi.org/10.1007/s12011-020-02157-0) | | Study key | d32385715 | ## Takeaway Magnesium supplementation can help lower blood pressure in people with type 2 diabetes, especially with higher doses or longer durations. ## The question Does magnesium supplementation affect blood pressure and obesity measures in patients with type 2 diabetes mellitus? ## Hypothesis The study aimed to evaluate the effects of magnesium supplementation on blood pressure and obesity measures in type 2 diabetes patients. ## Methods A meta-analysis of randomized clinical trials (RCTs) was conducted by searching major electronic databases (Web of Science, Cochrane library, PubMed, Scopus) up to October 15, 2019. Outcomes were pooled using a random-effects model and expressed as weighted mean differences (WMD) with 95% confidence intervals (CI). Heterogeneity, sensitivity analysis, and publication bias were also assessed. ## Results Pooling five RCTs showed that magnesium supplementation did not significantly affect body weight (WMD: -0.01 kg), BMI (WMD: -0.07), or waist circumference (WMD: 0.12). However, pooling seven RCTs showed a significant reduction in systolic blood pressure (WMD: -5.78 mmHg) and diastolic blood pressure (WMD: -2.50 mmHg). Subgroup analysis indicated that magnesium supplementation for more than 12 weeks, at doses higher than 300 mg/day, or in inorganic forms, significantly decreased both systolic and diastolic blood pressure. ## Conclusion Magnesium supplementation has beneficial effects on blood pressure in type 2 diabetes patients, independent of body weight status. ## Limitations The study suggests that further investigations are needed to provide more reliable evidence. ## Verbatim from the abstract > significant reduction of systolic and diastolic blood pressure in T2DM patients ## Effect of Magnesium Supplementation on Blood Pressure in Type 2 Diabetes Patients | Measure | WMD (mmHg) | | --- | --- | | Systolic BP Reduction | -5.78 | | Diastolic BP Reduction | -2.5 | *Weighted mean differences (WMD) in blood pressure reduction with magnesium supplementation compared to control groups in type 2 diabetes patients.* ## Where this study is used on Magellan This paper is one of the citations behind the evidence grade on the pages below. Grades are assigned from the published research and are independent of affiliate commissions. | Compound or device | Evidence grade | Graded pages | | --- | --- | --- | | Magnesium Glycinate | Moderate evidence | [Magnesium Glycinate](https://magellanlongevity.com/p/136.md) | ## Reference 1. **The Effects of Magnesium Supplementation on Blood Pressure Among Type 2 Diabetes Patients: a meta-analysis** Biol Trace Elem Res 2020 · [PMID 32385715](https://pubmed.ncbi.nlm.nih.gov/32385715/) · [DOI 10.1007/s12011-020-02157-0](https://doi.org/10.1007/s12011-020-02157-0) > significant reduction of systolic and diastolic blood pressure in T2DM patients ## Structured data ```json {"@context":"https://schema.org","@graph":[{"@type":"MedicalWebPage","@id":"https://magellanlongevity.com/study/d32385715.html#page","url":"https://magellanlongevity.com/study/d32385715.html","name":"The Effects of Magnesium Supplementation on Blood Pressure Among Type 2 Diabetes Patients: a meta-analysis","description":"Magnesium supplementation can help lower blood pressure in people with type 2 diabetes, especially with higher doses or longer durations.","inLanguage":"en","isPartOf":{"@type":"WebSite","name":"Magellan Longevity","url":"https://magellanlongevity.com/"},"author":{"@type":"Person","name":"Gabriel Radu, DO","jobTitle":"Physiatrist (PM&R)","identifier":[{"@type":"PropertyValue","name":"NPI","value":"1376861765"},{"@type":"PropertyValue","name":"NY medical license","value":"275110"}]},"publisher":{"@type":"Organization","name":"Magellan Longevity","url":"https://magellanlongevity.com/"},"encoding":{"@type":"MediaObject","encodingFormat":"text/markdown","contentUrl":"https://magellanlongevity.com/study/d32385715.md"},"dateModified":"2026-09-02"},{"@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://magellanlongevity.com/"},{"@type":"ListItem","position":2,"name":"Research map","item":"https://magellanlongevity.com/longevity-research-map.html"},{"@type":"ListItem","position":3,"name":"The Effects of Magnesium Supplementation on Blood Pressure…","item":"https://magellanlongevity.com/study/d32385715.html"}]},{"@type":"ScholarlyArticle","@id":"https://magellanlongevity.com/study/d32385715.html#study","name":"The Effects of Magnesium Supplementation on Blood Pressure Among Type 2 Diabetes Patients: a meta-analysis","headline":"The Effects of Magnesium Supplementation on Blood Pressure Among Type 2 Diabetes Patients: a meta-analysis","datePublished":"2020","isPartOf":{"@type":"Periodical","name":"Biol Trace Elem Res"},"identifier":"PMID:32385715","url":"https://pubmed.ncbi.nlm.nih.gov/32385715/","sameAs":"https://doi.org/10.1007/s12011-020-02157-0","abstract":"Magnesium supplementation can help lower blood pressure in people with type 2 diabetes, especially with higher doses or longer durations."}]} ``` ## Related on Magellan Longevity - [Magnesium Glycinate](https://magellanlongevity.com/p/136.md) — product graded on this and related evidence - [Evidence: enzymatic cofactor (300+ reactions)](https://magellanlongevity.com/study/s136.md) - [Magnesium Supplementation and Blood Pressure: A Systematic Review and Meta-Analysis of…](https://magellanlongevity.com/study/d41000008.md) - [Longevity research map](https://magellanlongevity.com/longevity-research-map.html) - [Evidence-based longevity supplements](https://magellanlongevity.com/longevity-supplements.md) ## Scope and disclosures Educational information, not medical advice. Nothing here is intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement or device, especially if you are pregnant, nursing, or taking medication. Editorial firewall: evidence grades are assigned from the published research and are independent of any affiliate commission. As an Amazon Associate, Magellan Longevity earns from qualifying purchases. Reviewed for accuracy by a board-certified physician (DO).