---
title: "Association of handgrip strength with all-cause mortality: a…"
description: "Stronger handgrip strength is linked to a lower risk of death from all causes in middle-aged and older Chinese adults, especially in younger men."
url: "https://magellanlongevity.com/study/d36064503.md"
canonical: "https://magellanlongevity.com/study/d36064503.html"
html: "https://magellanlongevity.com/study/d36064503.html"
type: "study"
study_key: "d36064503"
journal: "J Sci Med Sport"
year: 2022
pmid: "36064503"
doi: "10.1016/j.jsams.2022.08.005"
citations: 1
updated: 2026-09-02
author: "Gabriel Radu, DO"
author_credentials: "Physiatrist (PM&R). NY medical license 275110. NPI 1376861765."
publisher: "Magellan Longevity"
content_format: "markdown"
---

# Association of handgrip strength with all-cause mortality: a nationally longitudinal cohort study in China

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## Citation

| Field | Value |
| --- | --- |
| Journal | J Sci Med Sport |
| Year | 2022 |
| PMID | [36064503](https://pubmed.ncbi.nlm.nih.gov/36064503/) |
| DOI | [10.1016/j.jsams.2022.08.005](https://doi.org/10.1016/j.jsams.2022.08.005) |
| Study key | d36064503 |

## Takeaway

Stronger handgrip strength is linked to a lower risk of death from all causes in middle-aged and older Chinese adults, especially in younger men.

## The question

What is the association between handgrip strength and all-cause mortality among middle-aged and older Chinese adults?

## Hypothesis

The study hypothesized that handgrip strength would be associated with overall mortality risk among Chinese adults.

## Methods

This was a longitudinal cohort study using data from the China Health and Retirement Longitudinal Study (CHARLS). Handgrip strength was measured for both hands using a dynamometer. Logistic regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the association between handgrip strength and all-cause mortality, adjusting for various demographic and lifestyle factors. Deaths were ascertained through follow-up surveys.

## Results

Over an average follow-up of approximately 8 years, among 11,618 participants aged 45 and older, 1290 deaths were recorded. Greater handgrip strength was associated with a lower overall mortality risk. The adjusted ORs (comparing extreme tertiles) were 0.47 in men and 0.51 in women. This inverse association appeared stronger in younger men (OR = 0.29) compared to older men (OR = 0.49).

## Conclusion

Handgrip strength was inversely associated with the risk of all-cause mortality, particularly among younger men.

## Limitations

The abstract does not explicitly state limitations, but it suggests that further investigations are needed to understand the underlying mechanism of the observed association.

## Verbatim from the abstract

> handgrip strength was inversely associated with all-cause mortality risk

## Adjusted Odds Ratios for All-Cause Mortality by Handgrip Strength (Extreme Tertiles)

| Measure | Adjusted Odds Ratio |
| --- | --- |
| Men | 0.47 |
| Women | 0.51 |
| Younger Men | 0.29 |
| Older Men | 0.49 |

*Adjusted odds ratios for all-cause mortality, comparing extreme tertiles of handgrip strength, showing a stronger inverse association in younger men.*

## Where this study is used on Magellan

This paper is one of the citations behind the evidence grade on the pages below. Grades are assigned from the published research and are independent of affiliate commissions.

| Compound or device | Evidence grade | Graded pages |
| --- | --- | --- |
| Hand Grip Dynamometer Pro | Strong evidence | [Hand Grip Dynamometer Pro](https://magellanlongevity.com/p/162.md) |

## Reference

1. **Association of handgrip strength with all-cause mortality: a nationally longitudinal cohort study in China**
   J Sci Med Sport 2022 · [PMID 36064503](https://pubmed.ncbi.nlm.nih.gov/36064503/) · [DOI 10.1016/j.jsams.2022.08.005](https://doi.org/10.1016/j.jsams.2022.08.005)

   > handgrip strength was inversely associated with all-cause mortality risk

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- [Hand Grip Dynamometer Pro](https://magellanlongevity.com/p/162.md) — product graded on this and related evidence
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## Scope and disclosures

Educational information, not medical advice. Nothing here is intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement or device, especially if you are pregnant, nursing, or taking medication.

Editorial firewall: evidence grades are assigned from the published research and are independent of any affiliate commission. As an Amazon Associate, Magellan Longevity earns from qualifying purchases.

Reviewed for accuracy by a board-certified physician (DO).