--- title: "Effects of inspiratory muscle training on blood pressure and…" description: "Inspiratory muscle training may help lower blood pressure and improve sleep in people with obstructive sleep apnea, but more research is needed." url: "https://magellanlongevity.com/study/d36576599.md" canonical: "https://magellanlongevity.com/study/d36576599.html" html: "https://magellanlongevity.com/study/d36576599.html" type: "study" study_key: "d36576599" journal: "Sleep Breath" year: 2022 pmid: "36576599" doi: "10.1007/s11325-022-02773-1" citations: 1 updated: 2026-09-02 author: "Gabriel Radu, DO" author_credentials: "Physiatrist (PM&R). NY medical license 275110. NPI 1376861765." publisher: "Magellan Longevity" content_format: "markdown" --- # Effects of inspiratory muscle training on blood pressure and sleep in obstructive sleep apnea: a meta-analysis [Home](https://magellanlongevity.com/) › [Research map](https://magellanlongevity.com/longevity-research-map.html) › Effects of inspiratory muscle training on blood pressure… **HTML version:** https://magellanlongevity.com/study/d36576599.html · **In the Magellan app:** https://magellanlongevity.com/#/study/d36576599 ## Citation | Field | Value | | --- | --- | | Journal | Sleep Breath | | Year | 2022 | | PMID | [36576599](https://pubmed.ncbi.nlm.nih.gov/36576599/) | | DOI | [10.1007/s11325-022-02773-1](https://doi.org/10.1007/s11325-022-02773-1) | | Study key | d36576599 | ## Takeaway Inspiratory muscle training may help lower blood pressure and improve sleep in people with obstructive sleep apnea, but more research is needed. ## The question Does inspiratory muscle training (IMT) improve blood pressure and sleep in patients with obstructive sleep apnea (OSA)? ## Hypothesis Inspiratory muscle training (IMT) may reduce airway collapsibility and sympathetic output, potentially decreasing OSA severity and blood pressure. ## Methods This meta-analysis included seven randomized controlled trials (RCTs) with 160 patients with OSA. The researchers searched PubMed, EMBASE, Cochrane Library, Web of Science, and ClinicalTrials.gov for relevant RCTs published before November 2022. ## Results Compared to control groups, the IMT group showed significantly lower systolic blood pressure (mean difference [MD]: -10.77 mmHg), diastolic blood pressure (MD: -4.58 mmHg), plasma catecholamine levels (MD: -128.64 pg/mL), Pittsburgh Sleep Quality Index (MD: -3.06), and Epworth Sleepiness Scale score (MD: -4.37). No significant differences were found in the apnea-hypopnea index, forced vital capacity, ratio of forced expiratory volume in 1 second to forced vital capacity, or adverse effects. ## Conclusion Inspiratory muscle training improved blood pressure and sleep-related outcomes in patients with OSA without causing adverse effects, suggesting it could be a reasonable option for lowering blood pressure in this population. ## Limitations The level of certainty for the findings remains low, and additional studies with larger sample sizes and more rigorous designs are needed to increase this certainty. ## Verbatim from the abstract > the IMT group exhibited significantly lower systolic and diastolic blood pressure ## Mean Differences in Outcomes with Inspiratory Muscle Training vs. Control | Measure | Mean Difference | | --- | --- | | Systolic BP (mmHg) | -10.77 | | Diastolic BP (mmHg) | -4.58 | | Plasma Catecholamines (pg/mL) | -128.64 | | Pittsburgh Sleep Quality Index | -3.06 | | Epworth Sleepiness Scale | -4.37 | *Inspiratory muscle training significantly reduced systolic and diastolic blood pressure, plasma catecholamine levels, and improved sleep quality and daytime sleepiness compared to control groups.* ## Where this study is used on Magellan This paper is one of the citations behind the evidence grade on the pages below. Grades are assigned from the published research and are independent of affiliate commissions. | Compound or device | Evidence grade | Graded pages | | --- | --- | --- | | Inspiratory Muscle Strength Trainer | Moderate evidence | [Inspiratory Muscle Strength Trainer](https://magellanlongevity.com/p/165.md) | ## Reference 1. **Effects of inspiratory muscle training on blood pressure and sleep in obstructive sleep apnea: a meta-analysis** Sleep Breath 2022 · [PMID 36576599](https://pubmed.ncbi.nlm.nih.gov/36576599/) · [DOI 10.1007/s11325-022-02773-1](https://doi.org/10.1007/s11325-022-02773-1) > the IMT group exhibited significantly lower systolic and diastolic blood pressure ## Structured data ```json {"@context":"https://schema.org","@graph":[{"@type":"MedicalWebPage","@id":"https://magellanlongevity.com/study/d36576599.html#page","url":"https://magellanlongevity.com/study/d36576599.html","name":"Effects of inspiratory muscle training on blood pressure and sleep in obstructive sleep apnea: a meta-analysis","description":"Inspiratory muscle training may help lower blood pressure and improve sleep in people with obstructive sleep apnea, but more research is needed.","inLanguage":"en","isPartOf":{"@type":"WebSite","name":"Magellan Longevity","url":"https://magellanlongevity.com/"},"author":{"@type":"Person","name":"Gabriel Radu, DO","jobTitle":"Physiatrist (PM&R)","identifier":[{"@type":"PropertyValue","name":"NPI","value":"1376861765"},{"@type":"PropertyValue","name":"NY medical license","value":"275110"}]},"publisher":{"@type":"Organization","name":"Magellan Longevity","url":"https://magellanlongevity.com/"},"encoding":{"@type":"MediaObject","encodingFormat":"text/markdown","contentUrl":"https://magellanlongevity.com/study/d36576599.md"},"dateModified":"2026-09-02"},{"@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://magellanlongevity.com/"},{"@type":"ListItem","position":2,"name":"Research map","item":"https://magellanlongevity.com/longevity-research-map.html"},{"@type":"ListItem","position":3,"name":"Effects of inspiratory muscle training on blood pressure…","item":"https://magellanlongevity.com/study/d36576599.html"}]},{"@type":"ScholarlyArticle","@id":"https://magellanlongevity.com/study/d36576599.html#study","name":"Effects of inspiratory muscle training on blood pressure and sleep in obstructive sleep apnea: a meta-analysis","headline":"Effects of inspiratory muscle training on blood pressure and sleep in obstructive sleep apnea: a meta-analysis","datePublished":"2022","isPartOf":{"@type":"Periodical","name":"Sleep Breath"},"identifier":"PMID:36576599","url":"https://pubmed.ncbi.nlm.nih.gov/36576599/","sameAs":"https://doi.org/10.1007/s11325-022-02773-1","abstract":"Inspiratory muscle training may help lower blood pressure and improve sleep in people with obstructive sleep apnea, but more research is needed."}]} ``` ## Related on Magellan Longevity - [Inspiratory Muscle Strength Trainer](https://magellanlongevity.com/p/165.md) — product graded on this and related evidence - [Evidence: high-resistance breath loading](https://magellanlongevity.com/study/s165.md) - [Effects of high intensity inspiratory muscle training in patients with heart failure: a…](https://magellanlongevity.com/study/d37285766.md) - [Longevity research map](https://magellanlongevity.com/longevity-research-map.html) - [Evidence-based longevity supplements](https://magellanlongevity.com/longevity-supplements.md) ## Scope and disclosures Educational information, not medical advice. Nothing here is intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement or device, especially if you are pregnant, nursing, or taking medication. Editorial firewall: evidence grades are assigned from the published research and are independent of any affiliate commission. As an Amazon Associate, Magellan Longevity earns from qualifying purchases. Reviewed for accuracy by a board-certified physician (DO).