---
title: "Taurine as a biomarker for aging: A new avenue for translational…"
description: "Taurine levels decrease with age, and this deficiency may contribute to aging and age-related diseases, suggesting taurine supplementation could be…"
url: "https://magellanlongevity.com/study/d38435677.md"
canonical: "https://magellanlongevity.com/study/d38435677.html"
html: "https://magellanlongevity.com/study/d38435677.html"
type: "study"
study_key: "d38435677"
journal: "Adv Biomark Sci Technol"
year: 2023
pmid: "38435677"
doi: "10.1016/j.abst.2023.10.002"
citations: 1
updated: 2026-09-02
author: "Gabriel Radu, DO"
author_credentials: "Physiatrist (PM&R). NY medical license 275110. NPI 1376861765."
publisher: "Magellan Longevity"
content_format: "markdown"
---

# Taurine as a biomarker for aging: A new avenue for translational research

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**HTML version:** https://magellanlongevity.com/study/d38435677.html · **In the Magellan app:** https://magellanlongevity.com/#/study/d38435677

## Citation

| Field | Value |
| --- | --- |
| Journal | Adv Biomark Sci Technol |
| Year | 2023 |
| PMID | [38435677](https://pubmed.ncbi.nlm.nih.gov/38435677/) |
| DOI | [10.1016/j.abst.2023.10.002](https://doi.org/10.1016/j.abst.2023.10.002) |
| Study key | d38435677 |

## Takeaway

Taurine levels decrease with age, and this deficiency may contribute to aging and age-related diseases, suggesting taurine supplementation could be beneficial.

## The question

Does taurine shortage act as a driver and biomarker of aging, and what is its impact on a healthy lifespan?

## Hypothesis

The study by Singh et al. proposed that taurine shortage is a driver and biomarker of aging, and that early-life taurine insufficiency is linked to functional abnormalities in organs associated with age-related illnesses.

## Methods

The authors conducted a lifespan examination of various organisms, including mice, to assess the effects of taurine supplementation. They also analyzed multi-omics datasets (RNA sequencing, metabolomics) across different species after oral taurine supplementation combined with other interventions.

## Results

The abstract states that Singh et al. investigated taurine shortage as a driver and biomarker of aging and its impact on a healthy lifespan. It also notes that taurine deficiency in the elderly and the potential benefits of taurine supplements were considered, with a decrease in taurine concentration possibly due to loss of endogenous synthesis. The study analyzed the impacts of taurine supplementation and multi-omics data.

## Conclusion

The abstract suggests that taurine deficiency may contribute to the aging process and age-related illnesses, and that taurine supplementation could offer benefits. The study by Singh et al. explored taurine's role as a biomarker and driver of aging.

## Limitations

The abstract does not explicitly state any limitations of the study by Singh et al. or the review itself.

## Verbatim from the abstract

> abnormalities in numerous organs associated with age-related illnesses have been linked to early-life taurine insufficiency

## Where this study is used on Magellan

This paper is one of the citations behind the evidence grade on the pages below. Grades are assigned from the published research and are independent of affiliate commissions.

| Compound or device | Evidence grade | Graded pages |
| --- | --- | --- |
| Taurine | Moderate evidence | [Taurine](https://magellanlongevity.com/p/124.md) |

## Reference

1. **Taurine as a biomarker for aging: A new avenue for translational research**
   Adv Biomark Sci Technol 2023 · [PMID 38435677](https://pubmed.ncbi.nlm.nih.gov/38435677/) · [DOI 10.1016/j.abst.2023.10.002](https://doi.org/10.1016/j.abst.2023.10.002)

   > abnormalities in numerous organs associated with age-related illnesses have been linked to early-life taurine insufficiency

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## Related on Magellan Longevity

- [Taurine](https://magellanlongevity.com/p/124.md) — product graded on this and related evidence
- [Evidence: conditionally essential amino acid](https://magellanlongevity.com/study/s124.md)
- [Effects of taurine supplementation following eccentric exercise in young adults](https://magellanlongevity.com/study/taurine_muscle.md)
- [Longevity research map](https://magellanlongevity.com/longevity-research-map.html)
- [Evidence-based longevity supplements](https://magellanlongevity.com/longevity-supplements.md)

## Scope and disclosures

Educational information, not medical advice. Nothing here is intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement or device, especially if you are pregnant, nursing, or taking medication.

Editorial firewall: evidence grades are assigned from the published research and are independent of any affiliate commission. As an Amazon Associate, Magellan Longevity earns from qualifying purchases.

Reviewed for accuracy by a board-certified physician (DO).