--- title: "Effects of intermittent pneumatic compression on delayed onset…" description: "Intermittent pneumatic compression may help reduce muscle soreness and improve muscle recovery 48-72 hours after intense exercise." url: "https://magellanlongevity.com/study/d40094188.md" canonical: "https://magellanlongevity.com/study/d40094188.html" html: "https://magellanlongevity.com/study/d40094188.html" type: "study" study_key: "d40094188" journal: "PM R" year: 2025 pmid: "40094188" doi: "10.1002/pmrj.13377" citations: 1 updated: 2026-09-02 author: "Gabriel Radu, DO" author_credentials: "Physiatrist (PM&R). NY medical license 275110. NPI 1376861765." publisher: "Magellan Longevity" content_format: "markdown" --- # Effects of intermittent pneumatic compression on delayed onset muscle soreness and recovery [Home](https://magellanlongevity.com/) › [Research map](https://magellanlongevity.com/longevity-research-map.html) › Effects of intermittent pneumatic compression on delayed… **HTML version:** https://magellanlongevity.com/study/d40094188.html · **In the Magellan app:** https://magellanlongevity.com/#/study/d40094188 ## Citation | Field | Value | | --- | --- | | Journal | PM R | | Year | 2025 | | PMID | [40094188](https://pubmed.ncbi.nlm.nih.gov/40094188/) | | DOI | [10.1002/pmrj.13377](https://doi.org/10.1002/pmrj.13377) | | Study key | d40094188 | ## Takeaway Intermittent pneumatic compression may help reduce muscle soreness and improve muscle recovery 48-72 hours after intense exercise. ## The question Does intermittent pneumatic compression (IPC) effectively prevent or treat delayed-onset muscle soreness (DOMS) induced by plyometric exercise? ## Hypothesis The study aims to characterize the therapeutic effect of IPC on DOMS induced by plyometric exercise, suggesting an expected benefit. ## Methods Twenty healthy untrained male college students were randomized into an IPC group (n=10) and a control group (n=10). DOMS was induced by lower limb plyometric exercises. The IPC group received 15 minutes of treatment immediately and at 24, 48, and 72 hours post-exercise. Muscle soreness (Visual Analog Scale) and muscle condition (tensiomyography for maximal radial displacement, contraction time, and sustain time) were measured at various time points up to 96 hours post-exercise. ## Results The IPC group showed significantly improved recovery in muscle soreness (VAS), maximal radial displacement (Dm), and contraction time (Tc) compared to the control group. Significant differences were observed in VAS, Dm, and Tc at 48 and 72 hours post-exercise (all p < .05), and in sustain time (Ts) at 72 hours post-exercise (p < .05). A strong negative correlation between VAS score and Dm, and a positive correlation with Tc, delay time, relaxation time, and Ts were found 48 hours after exercise. ## Conclusion Intermittent pneumatic compression may mitigate exercise-induced DOMS following plyometric exercise, with peak therapeutic effects appearing 48-72 hours after exercise. ## Limitations The abstract does not explicitly state any limitations of the study. ## Verbatim from the abstract > the compression group demonstrated significantly improved recovery in muscle soreness ## Significant Differences Between IPC and Control Groups Post-Exercise | Measure | Significant Difference (1=Yes) | | --- | --- | | VAS (48h) | 1 | | VAS (72h) | 1 | | Dm (48h) | 1 | | Dm (72h) | 1 | | Tc (48h) | 1 | | Tc (72h) | 1 | | Ts (72h) | 1 | *This chart illustrates the time points at which significant differences (p < .05) were observed between the IPC and control groups for various muscle soreness and condition metrics. A value of 1 indicates a significant difference was found.* ## Where this study is used on Magellan This paper is one of the citations behind the evidence grade on the pages below. Grades are assigned from the published research and are independent of affiliate commissions. | Compound or device | Evidence grade | Graded pages | | --- | --- | --- | | Pneumatic Compression Recovery Boots | Emerging evidence | [Pneumatic Compression Recovery Boots](https://magellanlongevity.com/p/167.md) | ## Reference 1. **Effects of intermittent pneumatic compression on delayed onset muscle soreness and recovery** PM R 2025 · [PMID 40094188](https://pubmed.ncbi.nlm.nih.gov/40094188/) · [DOI 10.1002/pmrj.13377](https://doi.org/10.1002/pmrj.13377) > the compression group demonstrated significantly improved recovery in muscle soreness ## Structured data ```json {"@context":"https://schema.org","@graph":[{"@type":"MedicalWebPage","@id":"https://magellanlongevity.com/study/d40094188.html#page","url":"https://magellanlongevity.com/study/d40094188.html","name":"Effects of intermittent pneumatic compression on delayed onset muscle soreness and recovery","description":"Intermittent pneumatic compression may help reduce muscle soreness and improve muscle recovery 48-72 hours after intense exercise.","inLanguage":"en","isPartOf":{"@type":"WebSite","name":"Magellan Longevity","url":"https://magellanlongevity.com/"},"author":{"@type":"Person","name":"Gabriel Radu, DO","jobTitle":"Physiatrist (PM&R)","identifier":[{"@type":"PropertyValue","name":"NPI","value":"1376861765"},{"@type":"PropertyValue","name":"NY medical license","value":"275110"}]},"publisher":{"@type":"Organization","name":"Magellan Longevity","url":"https://magellanlongevity.com/"},"encoding":{"@type":"MediaObject","encodingFormat":"text/markdown","contentUrl":"https://magellanlongevity.com/study/d40094188.md"},"dateModified":"2026-09-02"},{"@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://magellanlongevity.com/"},{"@type":"ListItem","position":2,"name":"Research map","item":"https://magellanlongevity.com/longevity-research-map.html"},{"@type":"ListItem","position":3,"name":"Effects of intermittent pneumatic compression on delayed…","item":"https://magellanlongevity.com/study/d40094188.html"}]},{"@type":"ScholarlyArticle","@id":"https://magellanlongevity.com/study/d40094188.html#study","name":"Effects of intermittent pneumatic compression on delayed onset muscle soreness and recovery","headline":"Effects of intermittent pneumatic compression on delayed onset muscle soreness and recovery","datePublished":"2025","isPartOf":{"@type":"Periodical","name":"PM R"},"identifier":"PMID:40094188","url":"https://pubmed.ncbi.nlm.nih.gov/40094188/","sameAs":"https://doi.org/10.1002/pmrj.13377","abstract":"Intermittent pneumatic compression may help reduce muscle soreness and improve muscle recovery 48-72 hours after intense exercise."}]} ``` ## Related on Magellan Longevity - [Pneumatic Compression Recovery Boots](https://magellanlongevity.com/p/167.md) — product graded on this and related evidence - [Evidence: sequential limb compression](https://magellanlongevity.com/study/s167.md) - [The Effects of Intermittent Pneumatic Compression on Exercise-Induced Muscle Damage in…](https://magellanlongevity.com/study/d33418535.md) - [Longevity research map](https://magellanlongevity.com/longevity-research-map.html) - [Evidence-based longevity supplements](https://magellanlongevity.com/longevity-supplements.md) ## Scope and disclosures Educational information, not medical advice. Nothing here is intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement or device, especially if you are pregnant, nursing, or taking medication. Editorial firewall: evidence grades are assigned from the published research and are independent of any affiliate commission. As an Amazon Associate, Magellan Longevity earns from qualifying purchases. Reviewed for accuracy by a board-certified physician (DO).