---
title: "Evidence: lowers systolic/diastolic blood pressure"
description: "Quercetin supplementation can lower both systolic and diastolic blood pressure depending on the individual's blood pressure status."
url: "https://magellanlongevity.com/study/s105.md"
canonical: "https://magellanlongevity.com/study/s105.html"
html: "https://magellanlongevity.com/study/s105.html"
type: "study"
study_key: "s105"
journal: "Curr Probl Cardiol"
year: 2022
pmid: "35948195"
doi: "10.1016/j.cpcardiol.2022.101350"
citations: 1
updated: 2026-09-02
author: "Gabriel Radu, DO"
author_credentials: "Physiatrist (PM&R). NY medical license 275110. NPI 1376861765."
publisher: "Magellan Longevity"
content_format: "markdown"
---

# Evidence: lowers systolic/diastolic blood pressure

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**HTML version:** https://magellanlongevity.com/study/s105.html · **In the Magellan app:** https://magellanlongevity.com/#/study/s105

## Citation

| Field | Value |
| --- | --- |
| Journal | Curr Probl Cardiol |
| Year | 2022 |
| PMID | [35948195](https://pubmed.ncbi.nlm.nih.gov/35948195/) |
| DOI | [10.1016/j.cpcardiol.2022.101350](https://doi.org/10.1016/j.cpcardiol.2022.101350) |
| Study key | s105 |

## Takeaway

Quercetin supplementation can lower both systolic and diastolic blood pressure depending on the individual's blood pressure status.

## The question

Does quercetin supplementation affect systolic and diastolic blood pressure?

## Hypothesis

The meta-analysis aimed to summarize data on quercetin's impact on systolic blood pressure (SBP) and diastolic blood pressure (DBP) to clarify its effects.

## Methods

A meta-analysis was conducted by searching Medline, EMBASE, and Web of Science databases for randomized controlled trials assessing quercetin's impact on blood pressure until May 2022. A random-effects model was used for data analysis, and subgroup analysis explored effects in (pre)hypertensive and normotensive adults. Ten trials with 841 participants were included.

## Results

Quercetin supplementation significantly decreased SBP in the mixed population by 2.38 mmHg and in the normotensive subgroup by 1.82 mmHg. It also significantly decreased DBP in the (pre)hypertensive subgroup by 3.14 mmHg.

## Conclusion

Quercetin supplementation decreases blood pressure in both normotensive and (pre)hypertensive patients.

## Limitations

The abstract does not explicitly state any limitations of the meta-analysis.

## Verbatim from the abstract

> quercetin supplementation significantly decreased systolic blood pressure

## Quercetin's Effect on Blood Pressure

| Measure | Mean Difference (mmHg) |
| --- | --- |
| SBP (Mixed Population) | -2.38 |
| SBP (Normotensive) | -1.82 |
| DBP ((Pre)hypertensive) | -3.14 |

*Mean decrease in SBP and DBP with quercetin supplementation across different populations.*

## Where this study is used on Magellan

This paper is one of the citations behind the evidence grade on the pages below. Grades are assigned from the published research and are independent of affiliate commissions.

| Compound or device | Evidence grade | Graded pages |
| --- | --- | --- |
| Quercetin Capsules | Moderate evidence | [Quercetin Capsules](https://magellanlongevity.com/p/105.md) |

## Reference

1. **Evidence: lowers systolic/diastolic blood pressure**
   Curr Probl Cardiol 2022 · [PMID 35948195](https://pubmed.ncbi.nlm.nih.gov/35948195/) · [DOI 10.1016/j.cpcardiol.2022.101350](https://doi.org/10.1016/j.cpcardiol.2022.101350)

   > quercetin supplementation significantly decreased systolic blood pressure

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## Related on Magellan Longevity

- [Quercetin Capsules](https://magellanlongevity.com/p/105.md) — product graded on this and related evidence
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## Scope and disclosures

Educational information, not medical advice. Nothing here is intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement or device, especially if you are pregnant, nursing, or taking medication.

Editorial firewall: evidence grades are assigned from the published research and are independent of any affiliate commission. As an Amazon Associate, Magellan Longevity earns from qualifying purchases.

Reviewed for accuracy by a board-certified physician (DO).