--- title: "Evidence: quantifies handgrip-force biomarker" description: "Lower handgrip strength is linked to a higher risk of death in dialysis patients." url: "https://magellanlongevity.com/study/s162.md" canonical: "https://magellanlongevity.com/study/s162.html" html: "https://magellanlongevity.com/study/s162.html" type: "study" study_key: "s162" journal: "J Ren Nutr" year: 2019 pmid: "30827839" doi: "10.1053/j.jrn.2019.01.002" citations: 1 updated: 2026-09-02 author: "Gabriel Radu, DO" author_credentials: "Physiatrist (PM&R). NY medical license 275110. NPI 1376861765." publisher: "Magellan Longevity" content_format: "markdown" --- # Evidence: quantifies handgrip-force biomarker [Home](https://magellanlongevity.com/) › [Research map](https://magellanlongevity.com/longevity-research-map.html) › Evidence: quantifies handgrip-force biomarker **HTML version:** https://magellanlongevity.com/study/s162.html · **In the Magellan app:** https://magellanlongevity.com/#/study/s162 ## Citation | Field | Value | | --- | --- | | Journal | J Ren Nutr | | Year | 2019 | | PMID | [30827839](https://pubmed.ncbi.nlm.nih.gov/30827839/) | | DOI | [10.1053/j.jrn.2019.01.002](https://doi.org/10.1053/j.jrn.2019.01.002) | | Study key | s162 | ## Takeaway Lower handgrip strength is linked to a higher risk of death in dialysis patients. ## The question What is the association between handgrip strength (HGS) and all-cause mortality in patients with chronic kidney disease undergoing dialysis? ## Hypothesis The study hypothesized that there would be an association between handgrip strength and all-cause mortality in patients with chronic kidney disease undergoing dialysis. ## Methods This meta-analysis included 9 prospective cohort studies identified by searching PubMed and EMBASE databases up to December 2, 2018. The studies evaluated the association between handgrip strength and all-cause mortality. ## Results Patients with low HGS had a summary risk ratio of all-cause mortality of 1.88 compared to those with high HGS. For every 1-kg unit increase in HGS, the summary risk ratio of all-cause mortality was 0.95. ## Conclusion Low handgrip strength is associated with an increased risk of all-cause mortality in patients with chronic kidney disease undergoing dialysis. ## Limitations The abstract does not explicitly state any limitations of the meta-analysis. ## Verbatim from the abstract > Handgrip strength as a predictor of all-cause mortality ## Risk Ratio of All-Cause Mortality in Dialysis Patients | Measure | Risk Ratio | | --- | --- | | Low HGS vs. High HGS | 1.88 | | 1-kg HGS Increase | 0.95 | *Comparison of all-cause mortality risk ratios based on handgrip strength in patients with chronic kidney disease undergoing dialysis.* ## Where this study is used on Magellan This paper is one of the citations behind the evidence grade on the pages below. Grades are assigned from the published research and are independent of affiliate commissions. | Compound or device | Evidence grade | Graded pages | | --- | --- | --- | | Grip-Strength Dynamometer | Measurement tool | [Grip-Strength Dynamometer](https://magellanlongevity.com/p/153.md) | | Hand Grip Dynamometer Pro | Strong evidence | [Hand Grip Dynamometer Pro](https://magellanlongevity.com/p/162.md) | ## Reference 1. **Evidence: quantifies handgrip-force biomarker** J Ren Nutr 2019 · [PMID 30827839](https://pubmed.ncbi.nlm.nih.gov/30827839/) · [DOI 10.1053/j.jrn.2019.01.002](https://doi.org/10.1053/j.jrn.2019.01.002) > Handgrip strength as a predictor of all-cause mortality ## Structured data ```json {"@context":"https://schema.org","@graph":[{"@type":"MedicalWebPage","@id":"https://magellanlongevity.com/study/s162.html#page","url":"https://magellanlongevity.com/study/s162.html","name":"Evidence: quantifies handgrip-force biomarker","description":"Lower handgrip strength is linked to a higher risk of death in dialysis patients.","inLanguage":"en","isPartOf":{"@type":"WebSite","name":"Magellan Longevity","url":"https://magellanlongevity.com/"},"author":{"@type":"Person","name":"Gabriel Radu, DO","jobTitle":"Physiatrist (PM&R)","identifier":[{"@type":"PropertyValue","name":"NPI","value":"1376861765"},{"@type":"PropertyValue","name":"NY medical license","value":"275110"}]},"publisher":{"@type":"Organization","name":"Magellan Longevity","url":"https://magellanlongevity.com/"},"encoding":{"@type":"MediaObject","encodingFormat":"text/markdown","contentUrl":"https://magellanlongevity.com/study/s162.md"},"dateModified":"2026-09-02"},{"@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://magellanlongevity.com/"},{"@type":"ListItem","position":2,"name":"Research map","item":"https://magellanlongevity.com/longevity-research-map.html"},{"@type":"ListItem","position":3,"name":"Evidence: quantifies handgrip-force biomarker","item":"https://magellanlongevity.com/study/s162.html"}]},{"@type":"ScholarlyArticle","@id":"https://magellanlongevity.com/study/s162.html#study","name":"Evidence: quantifies handgrip-force biomarker","headline":"Evidence: quantifies handgrip-force biomarker","datePublished":"2019","isPartOf":{"@type":"Periodical","name":"J Ren Nutr"},"identifier":"PMID:30827839","url":"https://pubmed.ncbi.nlm.nih.gov/30827839/","sameAs":"https://doi.org/10.1053/j.jrn.2019.01.002","abstract":"Lower handgrip strength is linked to a higher risk of death in dialysis patients."}]} ``` ## Related on Magellan Longevity - [Grip-Strength Dynamometer](https://magellanlongevity.com/p/153.md) — product graded on this and related evidence - [Hand Grip Dynamometer Pro](https://magellanlongevity.com/p/162.md) — product graded on this and related evidence - [Evidence: Handgrip strength (muscle strength)](https://magellanlongevity.com/study/s153.md) - [Thresholds of handgrip strength for all-cause, cancer, and cardiovascular mortality: a…](https://magellanlongevity.com/study/d36332759.md) - [Association of Muscle Strength With All-Cause Mortality in the Oldest Old: a 28-country…](https://magellanlongevity.com/study/d39439054.md) - [Longevity research map](https://magellanlongevity.com/longevity-research-map.html) - [Evidence-based longevity supplements](https://magellanlongevity.com/longevity-supplements.md) ## Scope and disclosures Educational information, not medical advice. Nothing here is intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement or device, especially if you are pregnant, nursing, or taking medication. Editorial firewall: evidence grades are assigned from the published research and are independent of any affiliate commission. As an Amazon Associate, Magellan Longevity earns from qualifying purchases. Reviewed for accuracy by a board-certified physician (DO).