--- title: "Evidence: conductive Earth contact" description: "Connecting with the Earth through grounding may influence inflammation, immune responses, and wound healing by altering white blood cell counts and…" url: "https://magellanlongevity.com/study/s192.md" canonical: "https://magellanlongevity.com/study/s192.html" html: "https://magellanlongevity.com/study/s192.html" type: "study" study_key: "s192" journal: "J Inflamm Res" year: 2015 pmid: "25848315" doi: "10.2147/JIR.S69656" citations: 1 updated: 2026-09-02 author: "Gabriel Radu, DO" author_credentials: "Physiatrist (PM&R). NY medical license 275110. NPI 1376861765." publisher: "Magellan Longevity" content_format: "markdown" --- # Evidence: conductive Earth contact [Home](https://magellanlongevity.com/) › [Research map](https://magellanlongevity.com/longevity-research-map.html) › Evidence: conductive Earth contact **HTML version:** https://magellanlongevity.com/study/s192.html · **In the Magellan app:** https://magellanlongevity.com/#/study/s192 ## Citation | Field | Value | | --- | --- | | Journal | J Inflamm Res | | Year | 2015 | | PMID | [25848315](https://pubmed.ncbi.nlm.nih.gov/25848315/) | | DOI | [10.2147/JIR.S69656](https://doi.org/10.2147/JIR.S69656) | | Study key | s192 | ## Takeaway Connecting with the Earth through grounding may influence inflammation, immune responses, and wound healing by altering white blood cell counts and inflammatory molecules. ## The question What are the physiological and health effects of electrically conductive contact of the human body with the Earth's surface (grounding or earthing)? ## Hypothesis Grounding an organism produces measurable differences in the concentrations of white blood cells, cytokines, and other molecules involved in the inflammatory response, and can influence outcomes of studies on inflammation, wound healing, and tumorigenesis. ## Methods The report synthesizes multi-disciplinary research findings and presents several hypotheses based on current research results and understanding of electronic aspects of cell and tissue physiology, cell biology, biophysics, and biochemistry. It also references studies using delayed onset muscle soreness as an experimental injury to monitor immune responses under grounded versus ungrounded conditions. ## Results Electrically conductive contact with the Earth produces intriguing effects on physiology and health, relating to inflammation, immune responses, wound healing, and prevention and treatment of chronic inflammatory and autoimmune diseases. Grounding reduces pain and alters the numbers of circulating neutrophils and lymphocytes, and affects various circulating chemical factors related to inflammation. ## Conclusion Grounding appears to offer a new perspective for studying inflammation and is an important, often overlooked, factor in experimental animal studies that can influence outcomes related to inflammation, wound healing, and tumorigenesis. ## Limitations The report primarily informs researchers and alerts them to potential factors, rather than presenting new experimental data. It also highlights the need for researchers to consider the length of time and degree of grounding, implying these are often overlooked. ## Verbatim from the abstract > grounding produces measurable differences in concentrations of white blood cells and cytokines ## Where this study is used on Magellan This paper is one of the citations behind the evidence grade on the pages below. Grades are assigned from the published research and are independent of affiliate commissions. | Compound or device | Evidence grade | Graded pages | | --- | --- | --- | | Grounding / Earthing Sleep Mat | — | — | ## Reference 1. **Evidence: conductive Earth contact** J Inflamm Res 2015 · [PMID 25848315](https://pubmed.ncbi.nlm.nih.gov/25848315/) · [DOI 10.2147/JIR.S69656](https://doi.org/10.2147/JIR.S69656) > grounding produces measurable differences in concentrations of white blood cells and cytokines ## Structured data ```json {"@context":"https://schema.org","@graph":[{"@type":"MedicalWebPage","@id":"https://magellanlongevity.com/study/s192.html#page","url":"https://magellanlongevity.com/study/s192.html","name":"Evidence: conductive Earth contact","description":"Connecting with the Earth through grounding may influence inflammation, immune responses, and wound healing by altering white blood cell counts and…","inLanguage":"en","isPartOf":{"@type":"WebSite","name":"Magellan Longevity","url":"https://magellanlongevity.com/"},"author":{"@type":"Person","name":"Gabriel Radu, DO","jobTitle":"Physiatrist (PM&R)","identifier":[{"@type":"PropertyValue","name":"NPI","value":"1376861765"},{"@type":"PropertyValue","name":"NY medical license","value":"275110"}]},"publisher":{"@type":"Organization","name":"Magellan Longevity","url":"https://magellanlongevity.com/"},"encoding":{"@type":"MediaObject","encodingFormat":"text/markdown","contentUrl":"https://magellanlongevity.com/study/s192.md"},"dateModified":"2026-09-02"},{"@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://magellanlongevity.com/"},{"@type":"ListItem","position":2,"name":"Research map","item":"https://magellanlongevity.com/longevity-research-map.html"},{"@type":"ListItem","position":3,"name":"Evidence: conductive Earth contact","item":"https://magellanlongevity.com/study/s192.html"}]},{"@type":"ScholarlyArticle","@id":"https://magellanlongevity.com/study/s192.html#study","name":"Evidence: conductive Earth contact","headline":"Evidence: conductive Earth contact","datePublished":"2015","isPartOf":{"@type":"Periodical","name":"J Inflamm Res"},"identifier":"PMID:25848315","url":"https://pubmed.ncbi.nlm.nih.gov/25848315/","sameAs":"https://doi.org/10.2147/JIR.S69656","abstract":"Connecting with the Earth through grounding may influence inflammation, immune responses, and wound healing by altering white blood cell counts and inflammatory molecules."}]} ``` ## Related on Magellan Longevity - [Earthing: health implications of reconnecting the human body to the Earth's surface…](https://magellanlongevity.com/study/d22291721.md) - [Longevity research map](https://magellanlongevity.com/longevity-research-map.html) - [Evidence-based longevity supplements](https://magellanlongevity.com/longevity-supplements.md) ## Scope and disclosures Educational information, not medical advice. Nothing here is intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement or device, especially if you are pregnant, nursing, or taking medication. Editorial firewall: evidence grades are assigned from the published research and are independent of any affiliate commission. As an Amazon Associate, Magellan Longevity earns from qualifying purchases. Reviewed for accuracy by a board-certified physician (DO).