---
title: "Effects of taurine supplementation following eccentric exercise…"
description: "Taurine supplementation may help reduce muscle damage and oxidative stress and improve strength after eccentric exercise, but it does not affect…"
url: "https://magellanlongevity.com/study/taurine_muscle.md"
canonical: "https://magellanlongevity.com/study/taurine_muscle.html"
html: "https://magellanlongevity.com/study/taurine_muscle.html"
type: "study"
study_key: "taurine_muscle"
journal: "Appl Physiol Nutr Metab"
year: 2013
pmid: "24383513"
doi: "10.1139/apnm-2012-0229"
citations: 1
updated: 2026-09-02
author: "Gabriel Radu, DO"
author_credentials: "Physiatrist (PM&R). NY medical license 275110. NPI 1376861765."
publisher: "Magellan Longevity"
content_format: "markdown"
---

# Effects of taurine supplementation following eccentric exercise in young adults

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## Citation

| Field | Value |
| --- | --- |
| Journal | Appl Physiol Nutr Metab |
| Year | 2013 |
| PMID | [24383513](https://pubmed.ncbi.nlm.nih.gov/24383513/) |
| DOI | [10.1139/apnm-2012-0229](https://doi.org/10.1139/apnm-2012-0229) |
| Study key | taurine_muscle |

## Takeaway

Taurine supplementation may help reduce muscle damage and oxidative stress and improve strength after eccentric exercise, but it does not affect inflammation.

## The question

What are the effects of taurine supplementation on muscle performance, oxidative stress, and inflammation after eccentric exercise in young adult males?

## Hypothesis

The study hypothesized that taurine supplementation would affect muscle performance, oxidative stress, and inflammation response after eccentric exercise.

## Methods

Twenty-one male participants were randomly assigned to either a placebo (n=10) or taurine (n=11) group. After 14 days of supplementation, subjects performed eccentric exercise of the elbow flexors. Blood samples and muscle performance measurements were taken on days 1, 14, 16, 18, and 21 to analyze performance, muscle damage, oxidative stress, and inflammatory markers.

## Results

Taurine supplementation increased strength levels and thiol total content, while decreasing muscle soreness, lactate dehydrogenase, creatine kinase activity, and oxidative damage (xylenol and protein carbonyl). However, antioxidant enzymes (superoxide dismutase, catalase, gluthatione peroxidase) and inflammatory markers (tumor necrosis factor, IL-1β, and IL-10) were not altered compared to the placebo group.

## Conclusion

Taurine supplementation may improve performance and reduce muscle damage and oxidative stress after eccentric exercise, but it does not appear to decrease the inflammatory response.

## Limitations

The abstract does not explicitly state limitations of the study.

## Verbatim from the abstract

> taurine supplementation resulted in increased strength levels and decreased muscle soreness, creatine kinase activity, and oxidative damage

## Where this study is used on Magellan

This paper is one of the citations behind the evidence grade on the pages below. Grades are assigned from the published research and are independent of affiliate commissions.

| Compound or device | Evidence grade | Graded pages |
| --- | --- | --- |
| Taurine | Moderate evidence | [Taurine](https://magellanlongevity.com/p/124.md) |

## Reference

1. **Effects of taurine supplementation following eccentric exercise in young adults**
   Appl Physiol Nutr Metab 2013 · [PMID 24383513](https://pubmed.ncbi.nlm.nih.gov/24383513/) · [DOI 10.1139/apnm-2012-0229](https://doi.org/10.1139/apnm-2012-0229)

   > taurine supplementation resulted in increased strength levels and decreased muscle soreness, creatine kinase activity, and oxidative damage

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## Related on Magellan Longevity

- [Taurine](https://magellanlongevity.com/p/124.md) — product graded on this and related evidence
- [Evidence: conditionally essential amino acid](https://magellanlongevity.com/study/s124.md)
- [Taurine as a biomarker for aging: A new avenue for translational research](https://magellanlongevity.com/study/d38435677.md)
- [Longevity research map](https://magellanlongevity.com/longevity-research-map.html)
- [Evidence-based longevity supplements](https://magellanlongevity.com/longevity-supplements.md)

## Scope and disclosures

Educational information, not medical advice. Nothing here is intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement or device, especially if you are pregnant, nursing, or taking medication.

Editorial firewall: evidence grades are assigned from the published research and are independent of any affiliate commission. As an Amazon Associate, Magellan Longevity earns from qualifying purchases.

Reviewed for accuracy by a board-certified physician (DO).