linked All-cause mortality
The 25(OH)D level can be regarded as an aging marker because it is linearly associated with age and an independent mortality predictor.
J Gerontol A, 2019 · PubMed 30371905 DOI
Vitamin D
Vitamin D status is a strong biomarker of biological aging and all-cause mortality, and daily supplementation modestly lowers cancer death risk, helping extend healthspan particularly in older adults.
Research-backed interactions
inhibits Cancer mortality
Vitamin D supplementation reduced the risk of cancer death by 16%.
BMJ, 2019 · PubMed 31405892 DOI
requires Vitamin D receptor / Klotho
VDR genetic ablation promotes premature aging in mice... vitamin D3 homeostasis regulates physiological aging.
J Steroid Biochem Mol Biol, 2009 · PubMed 19500727 DOI
Get it naturally
Food & lifestyle routes to the same biology, each backed by a citation.
Sunlight / UVB on skin
UVB converts skin 7-dehydrocholesterol to vitamin D3 — the body's primary route.
During exposure to sunlight 7-dehydrocholesterol in the skin absorbs UV B radiation and is converted to previtamin D3 which in turn isomerizes into vitamin D3.
Dermatoendocrinol, 2013 · PubMed 24494042 DOI
Fatty fish (salmon, mackerel, herring)
Fish is the major food source of vitamin D; fatty fish raises serum 25(OH)D the most.
As the major food source of vitamin D, fish consumption increases concentrations of 25(OH)D.
Am J Clin Nutr, 2015 · PubMed 26354531 DOI
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Frequently asked
How does Vitamin D relate to longevity?
Vitamin D status is a strong biomarker of biological aging and all-cause mortality, and daily supplementation modestly lowers cancer death risk, helping extend healthspan particularly in older adults.
How is Vitamin D related to All-cause mortality?
The 25(OH)D level can be regarded as an aging marker because it is linearly associated with age and an independent mortality predictor.
How is Vitamin D related to Cancer mortality?
Vitamin D supplementation reduced the risk of cancer death by 16%.
How is Vitamin D related to Vitamin D receptor / Klotho?
VDR genetic ablation promotes premature aging in mice... vitamin D3 homeostasis regulates physiological aging.