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Heart & brain · evidence-graded

Omega-3 (EPA/DHA): heart, brain, and your Omega-3 Index

Long-chain omega-3s EPA and DHA are among the best-supported nutrients for cardiovascular and brain aging. Here is the evidence, and how to know your Omega-3 Index.

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Why your Omega-3 Index matters

EPA and DHA are anti-inflammatory fatty acids your body cannot make efficiently. A higher Omega-3 Index (the EPA+DHA percentage in red blood cells) tracks with better cardiovascular and brain aging — and you can measure it at home. Oily fish is the best food source; a quality fish-oil or algae supplement closes the gap.

Omega-3 supplements & testing, graded

Linked to mechanism and PubMed citations.

Omega-3 EPA/DHA Fish Oil

8 PubMed-linked studies

Slightly reduces coronary mortality and events. Research relevant to this mechanism is indexed on PubMed and linked below; it describes the…

Omega-3 Index Test

2 PubMed-linked studies

Low index linked to higher total mortality. Research relevant to this mechanism is indexed on PubMed and linked below; it describes the mechanism…

Educational information, not medical advice. Supplements are not intended to diagnose, treat, cure, or prevent any disease. Talk to your physician before starting any supplement, especially if you are pregnant, nursing, or taking medication.

Frequently asked questions

Does omega-3 help you live longer?

Higher omega-3 levels track with lower cardiovascular and all-cause mortality in large cohorts; trial effects are modest but consistent for heart health.

What is the omega-3 dose?

Many studies use roughly 1–2 g/day of combined EPA+DHA; aim for an Omega-3 Index of 8–12%.

What is the Omega-3 Index?

It is the percentage of EPA+DHA in your red blood cell membranes — a measurable marker you can test at home.

Fish oil vs algae oil?

Algae oil is a vegan EPA/DHA source; both raise the Omega-3 Index. Choose a third-party-tested product.

Know your Omega-3 Index

The evidence, the test, and the best sources.

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