MAGELLAN LONGEVITY
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Data dictionary

v1.0.064 fieldsCC BY 4.0

Every column of the Magellan Longevity Open Evidence Dataset, with its type, meaning and — the part that matters for reuse — exactly which source field it came from. Machine-readable copies of this page: JSON, Markdown, Frictionless datapackage.

Encoding is UTF-8 throughout. CSVs follow RFC 4180: comma-delimited, " escaped by doubling, one header row, LF line endings. Multi-value cells use ; with no spaces. An empty cell means the source does not record that value — it is never a zero, never a placeholder, and nothing is imputed.

Table 1 — products

130 rows × 32 fields. Primary key product_id. Files: products.csv, products.json, products.jsonl.

FieldTypeDescriptionProvenance
product_idintegerStable catalogue identifier. Resolves to https://magellanlongevity.com/p/<product_id>.htmldata.js products[].id
product_namestringRetail product name as listed on the site.data.js products[].name
category_idintegerStorefront category (1–7).data.js products[].cat
category_namestringHuman-readable category label.data.js categories
monograph_idstringCompound/device monograph the product inherits its evidence from. Many products share one monograph.data.js products[].mono
compound_or_devicestringTitle of that monograph — the active compound or device class actually studied.data.js monographs[].title
evidence_gradestringOne of six tier labels. See the rubric on https://magellanlongevity.com/data/index.html TIER + evidenceFor()
evidence_grade_letterstringShort letter form of the tier (A, B, C, C-, D).index.html TIER[].grade
evidence_tier_keystringMachine key for the tier: strong | moderate | emerging | preliminary | tool | refuted.index.html TIER
grade_sourcestringHow the grade was arrived at: curated_product (physician-reviewed, product-specific), curated_compound (physician-reviewed at the compound level), instrument_default (diagnostic/wearable graded as a measurement tool), provisional_from_citation_count (conservative fallback, capped below Strong).derived from EVID_PROD / EVID / isTool()
grade_rationalestringThe plain-language reason shown to readers for why this grade applies.index.html evidenceFor().reason
grade_caveatstringThe published caveat — where the evidence is weak, null, conflicted or industry-funded. Negative findings are retained deliberately.index.html EVID/EVID_PROD caveat
studied_dosestringThe dose range actually used in human trials, where a verified range exists. Empty where none has been established — never inferred.dosedata.js studyDose, else EVID.dose
studied_dose_sourcestringWhich source supplied studied_dose.derived
dietary_dosestringHow much of the compound is obtainable from food, where that is meaningful.dosedata.js foodDose
pathway_idstringMechanistic system key assigned to the product.data.js products[].sys
pathway_namestringHuman-readable pathway name (e.g. "NAD+ / Sirtuin Axis").index.html PATH_META
citation_countintegerNumber of peer-reviewed study records linked to this product's monograph.count of monographs[].studies
distinct_pmid_countintegerDistinct PubMed IDs among those citations (a few papers appear under more than one internal key).derived
studies_with_writeupintegerHow many of those citations have a full structured write-up in table 2.derived
pmidsstringSemicolon-separated PubMed IDs for every linked citation.derived
study_keysstringSemicolon-separated join keys into table 2 (studies.study_key).derived
key_finding_quotestringA verbatim sentence from the specific study used to justify the pathway assignment. Quoted, never paraphrased.data.js studies[].q
key_finding_pmidstringPubMed ID of that study.data.js studies[].pmid
key_finding_journalstringJournal of that study.data.js studies[].j
key_finding_yearintegerPublication year of that study.data.js studies[].y
key_finding_sourcestringWhether the key finding came from the curated pathway justification (product.why) or the first monograph citation.derived
listed_price_usdnumberTypical listed US price at the release date. A snapshot, not a live price.data.js products[].price
affiliate_search_urlstringAmazon search URL carrying the Associates tag. Commission does not affect the grade (editorial firewall).derived
product_page_urlstringCanonical static product page.derived
category_page_urlstringCanonical static category page.derived
monograph_page_urlstringCanonical molecule monograph page, where one is published. Empty otherwise.derived, validated against sitemap.xml

Table 2 — studies

2692 rows × 32 fields. Primary key study_key. Files: studies.csv, studies.json, studies.jsonl.

FieldTypeDescriptionProvenance
study_keystringInternal join key. Primary key of this table; join to products.study_keys.data.js studies key / study-writeups.js key
record_typestringcatalog_citation | catalog_citation_with_writeup | writeup_only.derived
pmidstringPubMed identifier.data.js studies[].pmid / write-up pmid
doistringDigital Object Identifier where recorded. Empty where the catalogue has none — never reconstructed.data.js studies[].doi
doi_urlstringResolvable https://doi.org/ URL.derived from doi
pubmed_urlstringResolvable PubMed URL.data.js studies[].url, else derived from pmid
titlestringArticle title as recorded.data.js studies[].t / write-up title
journalstringJournal name as recorded.data.js studies[].j
yearintegerPublication year.data.js studies[].y
primary_compoundstringTitle of the first monograph citing this study (deterministic, insertion order).derived
linked_compoundsstringSemicolon-separated titles of every monograph citing this study.derived
linked_monograph_idsstringSemicolon-separated monograph keys citing this study.derived
linked_monograph_countintegerHow many monographs cite it.derived
linked_product_idsstringSemicolon-separated product ids that inherit this citation.derived
linked_product_countintegerHow many catalogue products inherit this citation.derived
cited_by_monographbooleanFalse for records held in the catalogue but not yet attached to a monograph.derived
outcome_statementstringThe outcome in the source's own words: the write-up takeaway where one exists, otherwise the verbatim quoted finding.study-writeups.js takeaway / data.js studies[].q
outcome_statement_sourcestringWhich field outcome_statement came from.derived
reported_directionstringfavorable | mixed | no_difference | unfavorable | unclear. A coarse rule-based reading of the direction the source itself reports — NOT an independent appraisal. See the classifier notes below.derived
direction_rulestringWhich branch of the classifier fired.derived
direction_evidencestringThe exact phrase(s) that triggered the classification, so any row can be audited or rejected.derived
direction_basisstringWhich text was classified: the write-up conclusion+takeaway, or the catalogue quote fragment.derived
has_writeupbooleanWhether a full structured write-up exists.derived
writeup_urlstringCanonical study write-up page where one exists.derived
research_questionstringThe question the study set out to answer (write-ups only).study-writeups.js question
hypothesisstringThe stated hypothesis (write-ups only).study-writeups.js hypothesis
methodsstringDesign, population, dose and duration (write-ups only).study-writeups.js methods
resultsstringReported results (write-ups only).study-writeups.js results
conclusionstringThe authors' conclusion (write-ups only).study-writeups.js conclusion
limitationsstringStated limitations, retained verbatim including "none stated" (write-ups only).study-writeups.js limitations
source_filestringWhich source file(s) the row was assembled from.derived
is_primary_record_for_pmidbooleanTrue for exactly one row per PMID. Filter on this to de-duplicate to unique papers.derived

Controlled vocabularies

evidence_tier_key

ValueLabelLetterDefinitionRows
strongStrong evidenceAConsistent randomized human trials — or large, convergent human cohort data, sometimes backed by genetic (Mendelian) evidence — show a real benefit. That benefit is often a specific, measurable outcome (blood pressure, blood glucose, joint pain, muscle strength) rather than proof of a longer lifespan; each product’s page and caveat say exactly what the strong evidence is <i>for</i>.11
moderateModerate evidenceBSeveral human studies point the same way, but with limits — size, duration, funding, or mixed results.74
emergingEmerging evidenceCMechanism is plausible and early human data exists, but it is small, short, or not yet replicated.20
preliminaryPreliminaryC-Mostly mechanistic or animal data, or very few human studies. Interesting, not proven.4
toolMeasurement toolBA test or sensor. Graded on what the marker predicts and how reliably it measures it.20
refutedTested — did not workDAdequately tested in humans and the result was negative. This is not thin evidence — it is sufficient evidence pointing at no benefit, which is why it is graded below Preliminary rather than above it.1

grade_source

ValueMeaningRows
curated_productA physician-assigned grade specific to this product — used where products sharing a compound genuinely differ (for example nine wearables with different validation quality).26
curated_compoundA physician-assigned grade for the underlying compound, inherited by every product built on it.104
instrument_defaultA diagnostic or wearable, graded on what it measures and how well that marker predicts health rather than on a treatment effect.0
provisional_from_citation_countConservative fallback for uncurated entries, derived from the number of linked studies and capped below “Strong”.0

reported_direction

ValueMeaningRows
favorableThe source's own summary reports a benefit in the direction being tested.971
mixedBenefit and no-difference cues co-occur, or an unfavorable cue co-occurs with anything else.97
no_differenceThe source reports no significant difference, a failed endpoint, or an explicit absence of benefit.144
unfavorableThe source reports harm, or — for observational biomarker papers — that higher exposure tracks with worse outcomes.115
unclearNo rule fired. Usually a descriptive, mechanistic or review-style conclusion. NOT a null result.1365

How reported_direction is computed

reported_direction is produced by a deterministic, published rule cascade, not by a human or a language model. Unfavorable cues are checked first, then no-difference cues, then favorable cues; a negation guard suppresses a cue when it is preceded within 45 characters by no / not / without / free of / lack of / absence of / neither. Rows where an unfavorable cue co-occurs with any other cue, or where a no-difference cue co-occurs with a favorable cue, are labelled mixed. Rows where nothing fires are labelled unclear and are NOT counted as null results. For observational biomarker papers the "direction" is the direction reported for the biomarker, not for an intervention. Every row carries direction_evidence so the classification can be audited or discarded.

It is applied to the write-up conclusion plus takeaway where a structured write-up exists (314 rows), and to the verbatim catalogue quote otherwise (2378 rows). That difference is recorded per row in direction_basis, because a fragment quoted from an abstract supports a weaker inference than a full conclusion sentence.

If you disagree with the classifier, you can rebuild the column yourself: outcome_statement, conclusion and takeaway are all shipped verbatim.

Joining the tables

products.study_keys        --split(";")-->  studies.study_key
studies.linked_product_ids --split(";")-->  products.product_id

Table 2 contains 46 rows that repeat a PubMed identifier already present under another internal key. Filter is_primary_record_for_pmid == true to reduce it to 2646 unique papers before counting anything.

import pandas as pd
p = pd.read_csv("products.csv")
s = pd.read_csv("studies.csv")
unique_papers = s[s.is_primary_record_for_pmid]          # 2646 rows
strong = p[p.evidence_tier_key == "strong"]              # 11 rows
null_findings = s[s.reported_direction == "no_difference"]  # 144 rows

More

Dataset overview and downloads

Licence, citation, statistics and limitations.

All 130 grades in one table

Table 1 rendered for reading.

Research map

The citation graph, visualised.

Pathway universe

The vocabulary behind pathway_name.

Educational information, not medical advice. Evidence grades describe the strength of published human research — they are not clinical recommendations, and nothing in this dataset is intended to diagnose, treat, cure or prevent any disease. Talk to your own clinician before starting or stopping anything.