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Topical Pain Relief

Written and medically reviewed by , physiatrist · Last reviewed · How we grade

Every product below is graded on the strength of real human and mechanistic research and linked to its primary PubMed citations — independent of affiliate commissions. 5 products.

Voltaren Arthritis Pain Gel (Diclofenac 1%)

17 PubMed citations

Randomized trials and meta-analyses, including Cochrane reviews, indicate that topical diclofenac…

Capzasin-HP Capsaicin 0.1% Pain Relief Cream

17 PubMed citations

Randomized trials and meta-analyses show that topical capsaicin produces modest reductions in pain…

Aspercreme 4% Lidocaine Pain Relief Cream

22 PubMed citations

The best-supported use of topical lidocaine is localized neuropathic pain, especially postherpetic…

Biofreeze Menthol Pain Relief Gel

18 PubMed citations

Menthol is used for the temporary relief of minor muscle and joint pain, including strains,…

Salonpas Pain Relieving Patch (Methyl Salicylate + Menthol)

18 PubMed citations

Randomized trials of methyl-salicylate/menthol patches and menthol-based topical products show…

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