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Study summary · Environment, air, water & exposures

What are the effects of low-level indoor carbon dioxide (CO2) inhalation exposure on human health and psychomotor performance?

In one paragraph

Indoor CO2 Air-Quality Monitor (Environ Int 2018, PMID 30172928) — epidemiological studies showed an association between CO2 exposure beginning at 700 ppm and building-related symptoms, and respiratory symptoms in children exposed to over 1000 ppm, though other indoor pollutants might be involved. No numeric effect size is reported for Indoor CO2 Air-Quality Monitor in the source abstract.

Source: Environ Int 2018, PMID 30172928 ↗ · Research map · How Magellan grades evidence · evidence confidence: low

Environ Int · 2018 · PMID 30172928 · DOI 10.1016/j.envint.2018.08.059

Plain-English summary written and published by Magellan Longevity · medical review by Gabriel Radu, DO (physiatrist, NPI 1376861765). We summarize what the paper reported — we did not run this study.

The takeaway

Exposure to low levels of indoor carbon dioxide can negatively impact human physiology, cognitive function, and respiratory health.

The question

What are the effects of low-level indoor carbon dioxide (CO2) inhalation exposure on human health and psychomotor performance?

What they tested

The study does not explicitly state a hypothesis, but it aims to review existing literature to understand the effects of low-level CO2 exposure.

How they did it

The study conducted a review of scientific literature and documents concerning the effects of CO2 inhalation exposure on human health and psychomotor performance.

What they found

Linear physiological changes in circulatory, cardiovascular, and autonomic systems were observed with CO2 exposure from 500 to 5000 ppm. Short-term CO2 exposure starting at 1000 ppm affected cognitive performances like decision making and problem resolution. Epidemiological studies showed an association between CO2 exposure beginning at 700 ppm and building-related symptoms, and respiratory symptoms in children exposed to over 1000 ppm, though other indoor pollutants might be involved.

CO2 Concentration Thresholds for Observed Effects
Values shown: CO2 Concentration (ppm)
Physiological Changes500
Building-Related Symptoms700
Cognitive Performance Effects1000
Children's Respiratory Symptoms1000

This chart illustrates the minimum CO2 concentrations (in ppm) at which various health and performance effects were observed in the reviewed literature.

What it means

Low-level indoor CO2 exposure can lead to physiological changes, affect cognitive performance, and be associated with building-related and respiratory symptoms. Further research is needed on long-term effects on the autonomic system.

Limitations

The review notes that other indoor comorbid pollutants might be involved in the observed health effects, suggesting a potential confounder. It also highlights the need for further research on long-term effects.

“short-term CO2 exposure beginning at 1000 ppm affects decision making and problem resolution”— from the published abstract, Environ Int 2018

The paper at a glance

TitleEffects of low-level inhalation exposure to carbon dioxide indoors on human health and psychomotor performance
JournalEnviron Int
Year2018
PMID30172928 ↗
DOI10.1016/j.envint.2018.08.059 ↗
TopicEnvironment, air, water & exposures

Read the source: PubMed record (authors, abstract, full citation) ↗ · Publisher via doi.org ↗

Where Magellan uses this paper

This citation sits behind the evidence grade on the pages below. Grades are set from the research and are independent of affiliate commissions.

Indoor CO2 Air-Quality Monitor

Controlled human-exposure experiments have found that CO2 at concentrations common indoors (around 1,000-2,500 ppm) can reduce scores on tests of decision-making and higher-order cognition, and observational, real-world, and meta-analytic studies link higher ventilation (lower CO2) to better task performance in…

Indoor CO2 Air-Quality Monitor

An indoor CO2 (carbon dioxide) air-quality monitor measures the concentration of carbon dioxide in…

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Research describes the compound or intervention studied. It is not a claim about any specific product.

Cite this page

These citations point at this summary. To cite the original paper with its full author list, use the PubMed record or doi.org.

APA
Magellan Longevity. (2026). What are the effects of low-level indoor carbon dioxide (CO2) inhalation exposure on human health and psychomotor performance? [Plain-English summary of Environ Int 2018, PMID 30172928, DOI 10.1016/j.envint.2018.08.059]. Magellan Longevity. https://magellanlongevity.com/study/d30172928.html
BibTeX
@misc{magellan_d30172928, title = {What are the effects of low-level indoor carbon dioxide (CO2) inhalation exposure on human health and psychomotor performance?}, author = {{Magellan Longevity}}, year = {2026}, howpublished = {\url{https://magellanlongevity.com/study/d30172928.html}}, note = {Plain-English summary of PubMed PMID 30172928; DOI 10.1016/j.envint.2018.08.059; Environ Int 2018. Reviewed by Gabriel Radu, DO}, urldate = {2026-08-11} }
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How this summary was made. Every section above restates what the published abstract of PMID 30172928 reports — the question, the design, the numbers, the authors’ own conclusion and their stated limitations. We do not add claims the paper did not make, and we keep negative and no-effect findings in. Magellan’s evidence grades are set from research like this and never from affiliate commissions.

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Educational information, not medical advice. This is a plain-English summary of published research; it is not a treatment recommendation and nothing here is intended to diagnose, treat, cure, or prevent any disease. Individual studies can be wrong, and a single paper rarely settles a question. Talk to your physician before acting on any research, especially if you are pregnant, nursing, or taking medication.