Does MagteinPS, a formulation containing magnesium L-threonate, phosphatidylserine, and vitamins C and D, improve cognitive function in healthy Chinese adults?
Magnesium L-Threonate, a double-blind, placebo-controlled trial in 109 healthy Chinese adults (Nutrients 2022, PMID 36558392) — subjects receiving MagteinPS showed significant improvements over the control group in all five subcategories of "The Clinical Memory Test" and in overall memory quotient scores. Scope: 109 healthy Chinese adults, over 30 days, and the abstract states no limitations.
Source: Nutrients 2022, PMID 36558392 ↗ · Research map · How Magellan grades evidence · evidence confidence: low
Nutrients · 2022 · PMID 36558392 · DOI 10.3390/nu14245235
A supplement containing magnesium L-threonate, phosphatidylserine, and vitamins C and D improved memory and cognition in healthy Chinese adults, with older individuals showing more benefit.
The question
Does MagteinPS, a formulation containing magnesium L-threonate, phosphatidylserine, and vitamins C and D, improve cognitive function in healthy Chinese adults?
What they tested
MagteinPS will effectively raise magnesium levels in the brain and neurons, leading to improved memory and cognition.
How they did it
This was a double-blind, placebo-controlled study involving 109 healthy Chinese adults aged 18-65 years. Participants were randomly assigned to receive either 2 g/day of MagteinPS or a placebo (starch) for 30 days. Cognitive function was assessed using "The Clinical Memory Test" before and after the supplementation period.
What they found
Subjects receiving MagteinPS showed significant improvements over the control group in all five subcategories of "The Clinical Memory Test" and in overall memory quotient scores. Older participants demonstrated greater improvement compared to younger participants.
What it means
MagteinPS significantly improved memory and cognition in healthy Chinese adults.
Limitations
The abstract does not explicitly state any limitations of the study.
Where the published abstract does not list limitations, we say so rather than inventing them. Read the full paper on PubMed before drawing conclusions.
The paper at a glance
| Magellan’s evidence label | brain-penetrant magnesium (our label for this citation — see PubMed for the paper’s own title and authors) |
|---|---|
| Journal | Nutrients |
| Year | 2022 |
| PMID | 36558392 ↗ |
| DOI | 10.3390/nu14245235 ↗ |
| Topic | Brain, cognition & mood |
Read the source: PubMed record (authors, abstract, full citation) ↗ · Publisher via doi.org ↗
Where Magellan uses this paper
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Magnesium L-Threonate
In small randomized trials, magnesium-L-threonate improved composite cognition versus placebo in older adults with cognitive impairment and improved cognitive performance, sleep-quality scores and daytime functioning in healthy adults.
Magnesium L-threonate (also called L-threonic acid magnesium salt, L-TAMS, or the branded ingredient…
Research describes the compound or intervention studied. It is not a claim about any specific product.
Molecules & mechanisms in this paper
Each of these is named in the paper’s own words above. Open the monograph for the full mechanism and its other citations.
Cite this page
These citations point at this summary. To cite the original paper with its full author list, use the PubMed record or doi.org.
Magellan Longevity. (2026). Does MagteinPS, a formulation containing magnesium L-threonate, phosphatidylserine, and vitamins C and D, improve cognitive function in healthy Chinese adults? [Plain-English summary of Nutrients 2022, PMID 36558392, DOI 10.3390/nu14245235]. Magellan Longevity. https://magellanlongevity.com/study/s127.html@misc{magellan_s127,
title = {Does MagteinPS, a formulation containing magnesium L-threonate, phosphatidylserine, and vitamins C and D, improve cognitive function in healthy Chinese adults?},
author = {{Magellan Longevity}},
year = {2026},
howpublished = {\url{https://magellanlongevity.com/study/s127.html}},
note = {Plain-English summary of PubMed PMID 36558392; DOI 10.3390/nu14245235; Nutrients 2022. Reviewed by Gabriel Radu, DO},
urldate = {2026-08-11}
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