What are the effects of device-guided slow breathing (DGSB) and nondevice-guided slow breathing (NDGSB) on blood pressure levels in patients with hypertension?
Slow-Breathing Pacer Device, a systematic review and meta-analysis (Health Sci Rep 2022, PMID 35601033) — SBP variations showed a mean difference of -2.42 (443 individuals), and DBP variations showed a mean difference of -1.67 (443 individuals). DGSB did not significantly reduce SBP or DBP compared to usual care.
Source: Health Sci Rep 2022, PMID 35601033 ↗ · Research map · How Magellan grades evidence · evidence confidence: high
Health Sci Rep · 2022 · PMID 35601033 · DOI 10.1002/hsr2.636
Device-guided slow breathing did not significantly lower blood pressure in hypertensive patients compared to usual care.
The question
What are the effects of device-guided slow breathing (DGSB) and nondevice-guided slow breathing (NDGSB) on blood pressure levels in patients with hypertension?
What they tested
The study aims to summarize the effects of DGSB and NDGSB on blood pressure levels, implying an investigation into whether these methods reduce blood pressure.
How they did it
This systematic review and meta-analysis included randomized clinical trials involving hypertensive patients over 18 years old, of both sexes, with or without comorbidity or hypertensive medication. Studies compared groups performing DGSB and/or NDGSB with control conditions. The primary outcomes were systolic blood pressure (SBP) and diastolic blood pressure (DBP) values after interventions. A random effect model was used for quantitative analysis.
What they found
Twenty-two studies with 17,214 participants were included. DGSB did not significantly reduce SBP or DBP compared to usual care. For SBP, the mean difference was -2.13 mmHg (288 individuals), and for DBP, it was -0.90 mmHg (288 individuals). SBP variations showed a mean difference of -2.42 (443 individuals), and DBP variations showed a mean difference of -1.67 (443 individuals). Considerable heterogeneity was observed across studies.
| SBP (mmHg) | -2.13 | |
|---|---|---|
| DBP (mmHg) | -0.9 | |
| SBP Variation (mmHg) | -2.42 | |
| DBP Variation (mmHg) | -1.67 |
Mean differences in SBP and DBP, and their variations, when comparing device-guided slow breathing to usual care. Negative values indicate a reduction.
What it means
Device-guided slow breathing (DGSB) did not reduce blood pressure in hypertensive patients. Nondevice-guided slow breathing (NDGSB) is suggested as a potential future research direction.
Limitations
The abstract indicates considerable heterogeneity between the included studies, which may impact the generalizability of the findings.
The paper at a glance
| Title | Device and nondevice-guided slow breathing to reduce blood pressure in hypertensive patients: a meta-analysis |
|---|---|
| Journal | Health Sci Rep |
| Year | 2022 |
| PMID | 35601033 ↗ |
| DOI | 10.1002/hsr2.636 ↗ |
| Topic | Cardiovascular & vascular aging |
Read the source: PubMed record (authors, abstract, full citation) ↗ · Publisher via doi.org ↗
Where Magellan uses this paper
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Slow-Breathing Pacer Device
Non-drug blood pressure reduction. Research relevant to this mechanism is indexed on PubMed and linked below; it describes the mechanism rather than this specific product.
Molecules & mechanisms in this paper
Each of these is named in the paper’s own words above. Open the monograph for the full mechanism and its other citations.
Cite this page
These citations point at this summary. To cite the original paper with its full author list, use the PubMed record or doi.org.
Magellan Longevity. (2026). What are the effects of device-guided slow breathing (DGSB) and nondevice-guided slow breathing (NDGSB) on blood pressure levels in patients with hypertension? [Plain-English summary of Health Sci Rep 2022, PMID 35601033, DOI 10.1002/hsr2.636]. Magellan Longevity. https://magellanlongevity.com/study/d35601033.html@misc{magellan_d35601033,
title = {What are the effects of device-guided slow breathing (DGSB) and nondevice-guided slow breathing (NDGSB) on blood pressure levels in patients with hypertension?},
author = {{Magellan Longevity}},
year = {2026},
howpublished = {\url{https://magellanlongevity.com/study/d35601033.html}},
note = {Plain-English summary of PubMed PMID 35601033; DOI 10.1002/hsr2.636; Health Sci Rep 2022. Reviewed by Gabriel Radu, DO},
urldate = {2026-08-11}
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