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Study summary · Cardiovascular & vascular aging

Does quercetin supplementation affect systolic and diastolic blood pressure?

In one paragraph

Quercetin Capsules, a meta-analysis in 841 participants (Curr Probl Cardiol 2022, PMID 35948195) — quercetin supplementation significantly decreased SBP in the mixed population by 2.38 mmHg and in the normotensive subgroup by 1.82 mmHg. Scope: 841 participants, and the abstract states no limitations.

Source: Curr Probl Cardiol 2022, PMID 35948195 ↗ · Research map · How Magellan grades evidence · evidence confidence: medium

Curr Probl Cardiol · 2022 · PMID 35948195 · DOI 10.1016/j.cpcardiol.2022.101350

Plain-English summary written and published by Magellan Longevity · medical review by Gabriel Radu, DO (physiatrist, NPI 1376861765). We summarize what the paper reported — we did not run this study.

The takeaway

Quercetin supplementation can lower both systolic and diastolic blood pressure depending on the individual's blood pressure status.

The question

Does quercetin supplementation affect systolic and diastolic blood pressure?

What they tested

The meta-analysis aimed to summarize data on quercetin's impact on systolic blood pressure (SBP) and diastolic blood pressure (DBP) to clarify its effects.

How they did it

A meta-analysis was conducted by searching Medline, EMBASE, and Web of Science databases for randomized controlled trials assessing quercetin's impact on blood pressure until May 2022. A random-effects model was used for data analysis, and subgroup analysis explored effects in (pre)hypertensive and normotensive adults. Ten trials with 841 participants were included.

What they found

Quercetin supplementation significantly decreased SBP in the mixed population by 2.38 mmHg and in the normotensive subgroup by 1.82 mmHg. It also significantly decreased DBP in the (pre)hypertensive subgroup by 3.14 mmHg.

Quercetin's Effect on Blood Pressure
Values shown: Mean Difference (mmHg)
SBP (Mixed Population)-2.38
SBP (Normotensive)-1.82
DBP ((Pre)hypertensive)-3.14

Mean decrease in SBP and DBP with quercetin supplementation across different populations.

What it means

Quercetin supplementation decreases blood pressure in both normotensive and (pre)hypertensive patients.

Limitations

The abstract does not explicitly state any limitations of the meta-analysis.

Where the published abstract does not list limitations, we say so rather than inventing them. Read the full paper on PubMed before drawing conclusions.

“quercetin supplementation significantly decreased systolic blood pressure”— from the published abstract, Curr Probl Cardiol 2022

The paper at a glance

Magellan’s evidence labellowers systolic/diastolic blood pressure (our label for this citation — see PubMed for the paper’s own title and authors)
JournalCurr Probl Cardiol
Year2022
PMID35948195 ↗
DOI10.1016/j.cpcardiol.2022.101350 ↗
TopicCardiovascular & vascular aging

Read the source: PubMed record (authors, abstract, full citation) ↗ · Publisher via doi.org ↗

Where Magellan uses this paper

This citation sits behind the evidence grade on the pages below. Grades are set from the research and are independent of affiliate commissions.

Quercetin Capsules

Meta-analyses of randomized trials indicate quercetin produces a small blood-pressure reduction—on the order of 2–3 mmHg—most apparent at doses of at least 500 mg/day and in people with hypertension rather than normal blood pressure;

Quercetin Capsules

Quercetin is a flavonol, a plant polyphenol found abundantly in onions, apples, berries, capers, and…

Check price on Amazon ↗

Research describes the compound or intervention studied. It is not a claim about any specific product.

Molecules & mechanisms in this paper

Each of these is named in the paper’s own words above. Open the monograph for the full mechanism and its other citations.

Blood pressureQuercetin

Cite this page

These citations point at this summary. To cite the original paper with its full author list, use the PubMed record or doi.org.

APA
Magellan Longevity. (2026). Does quercetin supplementation affect systolic and diastolic blood pressure? [Plain-English summary of Curr Probl Cardiol 2022, PMID 35948195, DOI 10.1016/j.cpcardiol.2022.101350]. Magellan Longevity. https://magellanlongevity.com/study/s105.html
BibTeX
@misc{magellan_s105, title = {Does quercetin supplementation affect systolic and diastolic blood pressure?}, author = {{Magellan Longevity}}, year = {2026}, howpublished = {\url{https://magellanlongevity.com/study/s105.html}}, note = {Plain-English summary of PubMed PMID 35948195; DOI 10.1016/j.cpcardiol.2022.101350; Curr Probl Cardiol 2022. Reviewed by Gabriel Radu, DO}, urldate = {2026-08-11} }
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How this summary was made. Every section above restates what the published abstract of PMID 35948195 reports — the question, the design, the numbers, the authors’ own conclusion and their stated limitations. We do not add claims the paper did not make, and we keep negative and no-effect findings in. Magellan’s evidence grades are set from research like this and never from affiliate commissions.

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Educational information, not medical advice. This is a plain-English summary of published research; it is not a treatment recommendation and nothing here is intended to diagnose, treat, cure, or prevent any disease. Individual studies can be wrong, and a single paper rarely settles a question. Talk to your physician before acting on any research, especially if you are pregnant, nursing, or taking medication.