What is the association between handgrip strength and all-cause mortality among middle-aged and older Chinese adults?
Hand Grip Dynamometer Pro, a cohort study (J Sci Med Sport 2022, PMID 36064503) — over an average follow-up of approximately 8 years, among 11,618 participants aged 45 and older, 1290 deaths were recorded. The abstract for Hand Grip Dynamometer Pro states no limitations.
Source: J Sci Med Sport 2022, PMID 36064503 ↗ · Research map · How Magellan grades evidence · evidence confidence: medium
J Sci Med Sport · 2022 · PMID 36064503 · DOI 10.1016/j.jsams.2022.08.005
Stronger handgrip strength is linked to a lower risk of death from all causes in middle-aged and older Chinese adults, especially in younger men.
The question
What is the association between handgrip strength and all-cause mortality among middle-aged and older Chinese adults?
What they tested
The study hypothesized that handgrip strength would be associated with overall mortality risk among Chinese adults.
How they did it
This was a longitudinal cohort study using data from the China Health and Retirement Longitudinal Study (CHARLS). Handgrip strength was measured for both hands using a dynamometer. Logistic regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the association between handgrip strength and all-cause mortality, adjusting for various demographic and lifestyle factors. Deaths were ascertained through follow-up surveys.
What they found
Over an average follow-up of approximately 8 years, among 11,618 participants aged 45 and older, 1290 deaths were recorded. Greater handgrip strength was associated with a lower overall mortality risk. The adjusted ORs (comparing extreme tertiles) were 0.47 in men and 0.51 in women. This inverse association appeared stronger in younger men (OR = 0.29) compared to older men (OR = 0.49).
| Men | 0.47 | |
|---|---|---|
| Women | 0.51 | |
| Younger Men | 0.29 | |
| Older Men | 0.49 |
Adjusted odds ratios for all-cause mortality, comparing extreme tertiles of handgrip strength, showing a stronger inverse association in younger men.
What it means
Handgrip strength was inversely associated with the risk of all-cause mortality, particularly among younger men.
Limitations
The abstract does not explicitly state limitations, but it suggests that further investigations are needed to understand the underlying mechanism of the observed association.
Where the published abstract does not list limitations, we say so rather than inventing them. Read the full paper on PubMed before drawing conclusions.
The paper at a glance
| Title | Association of handgrip strength with all-cause mortality: a nationally longitudinal cohort study in China |
|---|---|
| Journal | J Sci Med Sport |
| Year | 2022 |
| PMID | 36064503 ↗ |
| DOI | 10.1016/j.jsams.2022.08.005 ↗ |
| Topic | Muscle, strength & physical function |
Read the source: PubMed record (authors, abstract, full citation) ↗ · Publisher via doi.org ↗
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Hand Grip Dynamometer Pro
Across large prospective cohorts (notably the 17-country PURE study and UK Biobank) and multiple meta-analyses pooling millions of participants, lower grip strength is consistently and independently associated with higher all-cause and cardiovascular mortality, and with cognitive decline, disability, sarcopenia and…
A hand-grip dynamometer measures the maximal isometric force generated by the muscles of the hand and…
Research describes the compound or intervention studied. It is not a claim about any specific product.
Molecules & mechanisms in this paper
Each of these is named in the paper’s own words above. Open the monograph for the full mechanism and its other citations.
Cite this page
These citations point at this summary. To cite the original paper with its full author list, use the PubMed record or doi.org.
Magellan Longevity. (2026). What is the association between handgrip strength and all-cause mortality among middle-aged and older Chinese adults? [Plain-English summary of J Sci Med Sport 2022, PMID 36064503, DOI 10.1016/j.jsams.2022.08.005]. Magellan Longevity. https://magellanlongevity.com/study/d36064503.html@misc{magellan_d36064503,
title = {What is the association between handgrip strength and all-cause mortality among middle-aged and older Chinese adults?},
author = {{Magellan Longevity}},
year = {2026},
howpublished = {\url{https://magellanlongevity.com/study/d36064503.html}},
note = {Plain-English summary of PubMed PMID 36064503; DOI 10.1016/j.jsams.2022.08.005; J Sci Med Sport 2022. Reviewed by Gabriel Radu, DO},
urldate = {2026-08-11}
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