What is the association between handgrip strength (HGS) and all-cause mortality in patients with chronic kidney disease undergoing dialysis?
Grip-Strength Dynamometer, a meta-analysis — patients with low HGS had a summary risk ratio of all-cause mortality of 1.88 compared to those with high HGS. The abstract for Grip-Strength Dynamometer states no limitations. Source: J Ren Nutr 2019, PMID 30827839.
Source: J Ren Nutr 2019, PMID 30827839 ↗ · Research map · How Magellan grades evidence · evidence confidence: medium
J Ren Nutr · 2019 · PMID 30827839 · DOI 10.1053/j.jrn.2019.01.002
Lower handgrip strength is linked to a higher risk of death in dialysis patients.
The question
What is the association between handgrip strength (HGS) and all-cause mortality in patients with chronic kidney disease undergoing dialysis?
What they tested
The study hypothesized that there would be an association between handgrip strength and all-cause mortality in patients with chronic kidney disease undergoing dialysis.
How they did it
This meta-analysis included 9 prospective cohort studies identified by searching PubMed and EMBASE databases up to December 2, 2018. The studies evaluated the association between handgrip strength and all-cause mortality.
What they found
Patients with low HGS had a summary risk ratio of all-cause mortality of 1.88 compared to those with high HGS. For every 1-kg unit increase in HGS, the summary risk ratio of all-cause mortality was 0.95.
| Low HGS vs. High HGS | 1.88 | |
|---|---|---|
| 1-kg HGS Increase | 0.95 |
Comparison of all-cause mortality risk ratios based on handgrip strength in patients with chronic kidney disease undergoing dialysis.
What it means
Low handgrip strength is associated with an increased risk of all-cause mortality in patients with chronic kidney disease undergoing dialysis.
Limitations
The abstract does not explicitly state any limitations of the meta-analysis.
Where the published abstract does not list limitations, we say so rather than inventing them. Read the full paper on PubMed before drawing conclusions.
The paper at a glance
| Magellan’s evidence label | quantifies handgrip-force biomarker (our label for this citation — see PubMed for the paper’s own title and authors) |
|---|---|
| Journal | J Ren Nutr |
| Year | 2019 |
| PMID | 30827839 ↗ |
| DOI | 10.1053/j.jrn.2019.01.002 ↗ |
| Topic | Muscle, strength & physical function |
Read the source: PubMed record (authors, abstract, full citation) ↗ · Publisher via doi.org ↗
Where Magellan uses this paper
This citation sits behind the evidence grade on the pages below. Grades are set from the research and are independent of affiliate commissions.
Grip-Strength Dynamometer
Across large prospective cohorts and meta-analyses, lower grip strength is consistently associated with higher all-cause and cardiovascular mortality, incident cardiovascular disease, disability, and, in some studies, cognitive decline and depression, often predicting outcomes as well as or better than systolic blood…
Hand Grip Dynamometer Pro
Across large prospective cohorts (notably the 17-country PURE study and UK Biobank) and multiple meta-analyses pooling millions of participants, lower grip strength is consistently and independently associated with higher all-cause and cardiovascular mortality, and with cognitive decline, disability, sarcopenia and…
A hand-grip (handgrip) dynamometer is a simple handheld device that measures the maximal isometric…
A hand-grip dynamometer measures the maximal isometric force generated by the muscles of the hand and…
Research describes the compound or intervention studied. It is not a claim about any specific product.
Molecules & mechanisms in this paper
Each of these is named in the paper’s own words above. Open the monograph for the full mechanism and its other citations.
Cite this page
These citations point at this summary. To cite the original paper with its full author list, use the PubMed record or doi.org.
Magellan Longevity. (2026). What is the association between handgrip strength (HGS) and all-cause mortality in patients with chronic kidney disease undergoing dialysis? [Plain-English summary of J Ren Nutr 2019, PMID 30827839, DOI 10.1053/j.jrn.2019.01.002]. Magellan Longevity. https://magellanlongevity.com/study/s162.html@misc{magellan_s162,
title = {What is the association between handgrip strength (HGS) and all-cause mortality in patients with chronic kidney disease undergoing dialysis?},
author = {{Magellan Longevity}},
year = {2026},
howpublished = {\url{https://magellanlongevity.com/study/s162.html}},
note = {Plain-English summary of PubMed PMID 30827839; DOI 10.1053/j.jrn.2019.01.002; J Ren Nutr 2019. Reviewed by Gabriel Radu, DO},
urldate = {2026-08-11}
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