What are the effects of taurine supplementation on muscle performance, oxidative stress, and inflammation after eccentric exercise in young adult males?
Taurine, studied in 10 participants (Appl Physiol Nutr Metab 2013, PMID 24383513) — however, antioxidant enzymes (superoxide dismutase, catalase, gluthatione peroxidase) and inflammatory markers (tumor necrosis factor, IL-1β, and IL-10) were not altered compared to the placebo group. Scope: 10 participants, and the abstract states no limitations.
Source: Appl Physiol Nutr Metab 2013, PMID 24383513 ↗ · Research map · How Magellan grades evidence · evidence confidence: low
Appl Physiol Nutr Metab · 2013 · PMID 24383513 · DOI 10.1139/apnm-2012-0229
Taurine supplementation may help reduce muscle damage and oxidative stress and improve strength after eccentric exercise, but it does not affect inflammation.
The question
What are the effects of taurine supplementation on muscle performance, oxidative stress, and inflammation after eccentric exercise in young adult males?
What they tested
The study hypothesized that taurine supplementation would affect muscle performance, oxidative stress, and inflammation response after eccentric exercise.
How they did it
Twenty-one male participants were randomly assigned to either a placebo (n=10) or taurine (n=11) group. After 14 days of supplementation, subjects performed eccentric exercise of the elbow flexors. Blood samples and muscle performance measurements were taken on days 1, 14, 16, 18, and 21 to analyze performance, muscle damage, oxidative stress, and inflammatory markers.
What they found
Taurine supplementation increased strength levels and thiol total content, while decreasing muscle soreness, lactate dehydrogenase, creatine kinase activity, and oxidative damage (xylenol and protein carbonyl). However, antioxidant enzymes (superoxide dismutase, catalase, gluthatione peroxidase) and inflammatory markers (tumor necrosis factor, IL-1β, and IL-10) were not altered compared to the placebo group.
What it means
Taurine supplementation may improve performance and reduce muscle damage and oxidative stress after eccentric exercise, but it does not appear to decrease the inflammatory response.
Limitations
The abstract does not explicitly state limitations of the study.
Where the published abstract does not list limitations, we say so rather than inventing them. Read the full paper on PubMed before drawing conclusions.
The paper at a glance
| Title | Effects of taurine supplementation following eccentric exercise in young adults |
|---|---|
| Journal | Appl Physiol Nutr Metab |
| Year | 2013 |
| PMID | 24383513 ↗ |
| DOI | 10.1139/apnm-2012-0229 ↗ |
| Topic | Immunity, inflammation & resilience |
Read the source: PubMed record (authors, abstract, full citation) ↗ · Publisher via doi.org ↗
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Taurine
A landmark 2023 study reported that taurine declines with age in mice, monkeys, and humans and that supplementation extended lifespan and healthspan in animals by reducing cellular senescence, mitochondrial dysfunction, DNA damage, and inflammation—but no randomized trial has yet shown that taurine slows aging in…
Taurine (2-aminoethanesulfonic acid) is a conditionally essential, sulfur-containing amino acid that is…
Research describes the compound or intervention studied. It is not a claim about any specific product.
Molecules & mechanisms in this paper
Each of these is named in the paper’s own words above. Open the monograph for the full mechanism and its other citations.
Cite this page
These citations point at this summary. To cite the original paper with its full author list, use the PubMed record or doi.org.
Magellan Longevity. (2026). What are the effects of taurine supplementation on muscle performance, oxidative stress, and inflammation after eccentric exercise in young adult males? [Plain-English summary of Appl Physiol Nutr Metab 2013, PMID 24383513, DOI 10.1139/apnm-2012-0229]. Magellan Longevity. https://magellanlongevity.com/study/taurine_muscle.html@misc{magellan_taurine_muscle,
title = {What are the effects of taurine supplementation on muscle performance, oxidative stress, and inflammation after eccentric exercise in young adult males?},
author = {{Magellan Longevity}},
year = {2026},
howpublished = {\url{https://magellanlongevity.com/study/taurine_muscle.html}},
note = {Plain-English summary of PubMed PMID 24383513; DOI 10.1139/apnm-2012-0229; Appl Physiol Nutr Metab 2013. Reviewed by Gabriel Radu, DO},
urldate = {2026-08-11}
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