Does taurine shortage act as a driver and biomarker of aging, and what is its impact on a healthy lifespan?
Taurine, an animal study (Adv Biomark Sci Technol 2023, PMID 38435677) — the study by Singh et al. explored taurine's role as a biomarker and driver of aging. No numeric effect size is reported for Taurine in the source abstract.
Source: Adv Biomark Sci Technol 2023, PMID 38435677 ↗ · Research map · How Magellan grades evidence · evidence confidence: low
Adv Biomark Sci Technol · 2023 · PMID 38435677 · DOI 10.1016/j.abst.2023.10.002
Taurine levels decrease with age, and this deficiency may contribute to aging and age-related diseases, suggesting taurine supplementation could be beneficial.
The question
Does taurine shortage act as a driver and biomarker of aging, and what is its impact on a healthy lifespan?
What they tested
The study by Singh et al. proposed that taurine shortage is a driver and biomarker of aging, and that early-life taurine insufficiency is linked to functional abnormalities in organs associated with age-related illnesses.
How they did it
The authors conducted a lifespan examination of various organisms, including mice, to assess the effects of taurine supplementation. They also analyzed multi-omics datasets (RNA sequencing, metabolomics) across different species after oral taurine supplementation combined with other interventions.
What they found
The abstract states that Singh et al. investigated taurine shortage as a driver and biomarker of aging and its impact on a healthy lifespan. It also notes that taurine deficiency in the elderly and the potential benefits of taurine supplements were considered, with a decrease in taurine concentration possibly due to loss of endogenous synthesis. The study analyzed the impacts of taurine supplementation and multi-omics data.
What it means
The abstract suggests that taurine deficiency may contribute to the aging process and age-related illnesses, and that taurine supplementation could offer benefits. The study by Singh et al. explored taurine's role as a biomarker and driver of aging.
Limitations
The abstract does not explicitly state any limitations of the study by Singh et al. or the review itself.
Where the published abstract does not list limitations, we say so rather than inventing them. Read the full paper on PubMed before drawing conclusions.
The paper at a glance
| Title | Taurine as a biomarker for aging: A new avenue for translational research |
|---|---|
| Journal | Adv Biomark Sci Technol |
| Year | 2023 |
| PMID | 38435677 ↗ |
| DOI | 10.1016/j.abst.2023.10.002 ↗ |
| Topic | General aging biology & healthspan |
Read the source: PubMed record (authors, abstract, full citation) ↗ · Publisher via doi.org ↗
Where Magellan uses this paper
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Taurine
A landmark 2023 study reported that taurine declines with age in mice, monkeys, and humans and that supplementation extended lifespan and healthspan in animals by reducing cellular senescence, mitochondrial dysfunction, DNA damage, and inflammation—but no randomized trial has yet shown that taurine slows aging in…
Taurine (2-aminoethanesulfonic acid) is a conditionally essential, sulfur-containing amino acid that is…
Research describes the compound or intervention studied. It is not a claim about any specific product.
Cite this page
These citations point at this summary. To cite the original paper with its full author list, use the PubMed record or doi.org.
Magellan Longevity. (2026). Does taurine shortage act as a driver and biomarker of aging, and what is its impact on a healthy lifespan? [Plain-English summary of Adv Biomark Sci Technol 2023, PMID 38435677, DOI 10.1016/j.abst.2023.10.002]. Magellan Longevity. https://magellanlongevity.com/study/d38435677.html@misc{magellan_d38435677,
title = {Does taurine shortage act as a driver and biomarker of aging, and what is its impact on a healthy lifespan?},
author = {{Magellan Longevity}},
year = {2026},
howpublished = {\url{https://magellanlongevity.com/study/d38435677.html}},
note = {Plain-English summary of PubMed PMID 38435677; DOI 10.1016/j.abst.2023.10.002; Adv Biomark Sci Technol 2023. Reviewed by Gabriel Radu, DO},
urldate = {2026-08-11}
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